phosphoinositide-3-kinase, catalytic, beta polypeptide

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Synonym

PI3-kinase p110 subunit beta, MGC133043, p110-BETA, PI3Kbeta, PIK3CB, PIK3C1, DKFZp779K1237

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:51 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:17.60 artery/aorta:60 vein:66.60 lymphnode:40.40 peripheral blood:18.20 spleen:- thymus:- bone marrow:157.40 adipose:- bone:25.60 skin:96
GeneChip cerebrum:4.10 cerebellum:4.20 brain stem:4.14 corpus callosum/glia:4.21 pineal gland:- peripheral nerve:3.95 spine:4.13 retina:- eye:- artery/aorta:4.02 vein:3.75 lymphnode:4.70 peripheral blood:- spleen:4.98 thymus:5.30 bone marrow:5.19 adipose:4.27 bone:- skin:4.06
CAGE cerebrum:3.56 cerebellum:- brain stem:3.72 corpus callosum/glia:3.41 pineal gland:3.24 peripheral nerve:- spine:3.33 retina:- eye:- artery/aorta:2.94 vein:3.15 lymphnode:3.08 peripheral blood:- spleen:3.17 thymus:3.41 bone marrow:- adipose:3.20 bone:- skin:-
RNA-seq cerebrum:3.69 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.40 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.13 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:25.50 prostate:33.80 ovary:37.30 testis:17.30 heart:- muscle:20.10 esophagus:- stomach:21.20 intestine:32.40 colon:76.30     liver/hepato:21.10        lung:19.60    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:46.50 salivary:-
GeneChip uterus:4.09 placenta:4.88 prostate:4.60 ovary:4.32 testis:3.61 heart:4.13 muscle:4.02 esophagus:4.17 stomach:4.57 intestine:4.51 colon:4.47 liver/hepato:4.31 lung:4.41 bladder:- kidney:4.74 pituitary:4.08 thyroid/parathyroid:5.38 adrenal gland:4.29 pancreas:4.10 breast:4.75 salivary:4.55
CAGE uterus:3.21 placenta:3.72 prostate:3.07 ovary:2.81 testis:2.70 heart:3.09 muscle:3.16 esophagus:3.21 stomach:- intestine:3.70 colon:3.32     liver/hepato:2.91    lung:3.16 bladder:3.18 kidney:3.49 pituitary:3.02 thyroid/parathyroid:3.81 adrenal gland:- pancreas:3.61 breast:2.41 salivary:3.77
RNA-seq uterus:- placenta:- prostate:3.08 ovary:2.52 testis:2.85 heart:3.14 muscle:3.12 esophagus:- stomach:- intestine:- colon:2.95     liver/hepato:2.08        lung:2.36    bladder:- kidney:3.41 pituitary:- thyroid/parathyroid:3.72 adrenal gland:1.93 pancreas:- breast:3.20 salivary:-

IDs

Refseq ID NM_006219
Gene ID 5291
Unigene ID Hs.239818
Probe set ID 217620_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000051382
GTEx ID ENSG00000051382

Orthologous Gene

Mouse[1]  NM_029094
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0006914  autophagy
GO:0007596  blood coagulation
GO:0016477  cell migration
GO:0006874  cellular calcium ion homeostasis
GO:0006935  chemotaxis
GO:0040016  embryonic cleavage
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007156  homophilic cell adhesion
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0050900  leukocyte migration
GO:0048011  nerve growth factor receptor signaling pathway
GO:0006661  phosphatidylinositol biosynthetic process
GO:0014065  phosphoinositide 3-kinase cascade
GO:0048015  phosphoinositide-mediated signaling
GO:0006644  phospholipid metabolic process
GO:0030168  platelet activation
GO:0070527  platelet aggregation
GO:0010508  positive regulation of autophagy
GO:0001952  regulation of cell-matrix adhesion
GO:0007165  signal transduction
GO:0050852  T cell receptor signaling pathway
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005829  cytosol
GO:0005634  nucleus
GO:0005942  phosphoinositide 3-kinase complex
GO:0005886  plasma membrane

Molecular Function

GO:0016303  1-phosphatidylinositol-3-kinase activity
GO:0005524  ATP binding
GO:0043560  insulin receptor substrate binding
GO:0046934  phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0035005  phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035004  phosphoinositide 3-kinase activity
GO:0005515  protein binding