phosphoinositide-3-kinase, catalytic, delta polypeptide

jump to detail

Synonym

PIK3CD, PI3-kinase p110 subunit delta, p110D, p110delta

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:15.40 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:47 artery/aorta:30 vein:133.30 lymphnode:141.50 peripheral blood:109.30 spleen:170.20 thymus:77.30 bone marrow:157.40 adipose:- bone:25.60 skin:28.80
GeneChip cerebrum:6.31 cerebellum:6.07 brain stem:6.31 corpus callosum/glia:6.41 pineal gland:- peripheral nerve:6.57 spine:6.25 retina:- eye:- artery/aorta:6.64 vein:6.21 lymphnode:8.75 peripheral blood:- spleen:9.27 thymus:8.44 bone marrow:8.87 adipose:6.74 bone:- skin:6.21
CAGE cerebrum:1.57 cerebellum:- brain stem:2.18 corpus callosum/glia:2.38 pineal gland:0.86 peripheral nerve:- spine:2.09 retina:- eye:- artery/aorta:2.17 vein:3.91 lymphnode:4.15 peripheral blood:- spleen:3.99 thymus:3.53 bone marrow:- adipose:1.76 bone:- skin:-
RNA-seq cerebrum:1.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.58 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.26 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:- prostate:11.30 ovary:- testis:38.90 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:- colon:67.80     liver/hepato:10.60        lung:29.30    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:55.80 salivary:-
GeneChip uterus:6.42 placenta:5.98 prostate:6.10 ovary:6.72 testis:6.39 heart:6 muscle:5.43 esophagus:6.29 stomach:6.74 intestine:6.42 colon:6.54 liver/hepato:6.42 lung:7.43 bladder:- kidney:6.62 pituitary:5.93 thyroid/parathyroid:6.64 adrenal gland:6.24 pancreas:6.33 breast:6.72 salivary:6.33
CAGE uterus:1.69 placenta:1.90 prostate:1.86 ovary:1.44 testis:1.83 heart:1.59 muscle:0.52 esophagus:1.86 stomach:- intestine:2.17 colon:2.26     liver/hepato:1.76    lung:2.73 bladder:1.45 kidney:1.38 pituitary:0.86 thyroid/parathyroid:1.17 adrenal gland:- pancreas:0.58 breast:1.36 salivary:2.06
RNA-seq uterus:- placenta:- prostate:1.63 ovary:1.28 testis:1.65 heart:0.68 muscle:0.34 esophagus:- stomach:- intestine:- colon:1.31     liver/hepato:0.53        lung:2.49    bladder:- kidney:1.20 pituitary:- thyroid/parathyroid:0.88 adrenal gland:3.81 pancreas:- breast:1.23 salivary:-

IDs

Refseq ID NM_005026
Gene ID 5293
Unigene ID Hs.518451
Probe set ID 203879_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171608
GTEx ID ENSG00000171608

Orthologous Gene

Mouse[18]  NM_001029837, NM_001164049, NM_001164050, NM_001164051, NM_001164052, NM_008840
Rat[1]  NM_001108978, NM_001164049, NM_001164050, NM_001164051, NM_001164052, NM_008840

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0042113  B cell activation
GO:0001782  B cell homeostasis
GO:0050853  B cell receptor signaling pathway
GO:0001816  cytokine production
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0002551  mast cell chemotaxis
GO:0043303  mast cell degranulation
GO:0060374  mast cell differentiation
GO:0030101  natural killer cell activation
GO:0001779  natural killer cell differentiation
GO:0048011  nerve growth factor receptor signaling pathway
GO:0030593  neutrophil chemotaxis
GO:0006661  phosphatidylinositol biosynthetic process
GO:0014065  phosphoinositide 3-kinase cascade
GO:0048015  phosphoinositide-mediated signaling
GO:0006644  phospholipid metabolic process
GO:0006468  protein amino acid phosphorylation
GO:0002679  respiratory burst during defense response
GO:0007165  signal transduction
GO:0042110  T cell activation
GO:0010818  T cell chemotaxis
GO:0030217  T cell differentiation
GO:0050852  T cell receptor signaling pathway

Cellular Component

GO:0005829  cytosol
GO:0005942  phosphoinositide 3-kinase complex
GO:0005886  plasma membrane

Molecular Function

GO:0016303  1-phosphatidylinositol-3-kinase activity
GO:0005524  ATP binding
GO:0046934  phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0035005  phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035004  phosphoinositide 3-kinase activity
GO:0005515  protein binding