phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

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Synonym

PIP5KIII, PtdIns(4)P-5-kinase isoform 2-alpha, PtdIns(4)P-5-kinase C isoform, PIP5KII-alpha, Diphosphoinositide kinase 2-alpha, PtdIns(4)P-5-kinase B isoform, PIP5K2A, PIP5K2, PIPK

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:139.80 cerebellum:138.50 brain stem:- corpus callosum/glia:233.30 pineal gland:148.30 peripheral nerve:30.70 spine:112.30 retina:118.60 eye:52.90 artery/aorta:179.90 vein:266.60 lymphnode:60.70 peripheral blood:273.30 spleen:378.10 thymus:270.60 bone marrow:98.40 adipose:403.30 bone:511.80 skin:259.20
GeneChip cerebrum:9.78 cerebellum:8 brain stem:10.14 corpus callosum/glia:10.70 pineal gland:- peripheral nerve:7.86 spine:10.04 retina:- eye:- artery/aorta:7.62 vein:7.80 lymphnode:8.77 peripheral blood:- spleen:8.86 thymus:8.15 bone marrow:9.17 adipose:7.45 bone:- skin:7.31
CAGE cerebrum:5.48 cerebellum:- brain stem:6.29 corpus callosum/glia:6.60 pineal gland:3.16 peripheral nerve:- spine:6.08 retina:- eye:- artery/aorta:4.53 vein:4.52 lymphnode:4.76 peripheral blood:- spleen:5.04 thymus:4.41 bone marrow:- adipose:4.04 bone:- skin:-
RNA-seq cerebrum:7.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.58 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.17 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:473.90 placenta:214.90 prostate:123.90 ovary:149.10 testis:268.20 heart:191.60 muscle:20.10 esophagus:- stomach:212.40 intestine:388.80 colon:262.90     liver/hepato:126.70        lung:151.50    bladder:2386.60 kidney:239.10 pituitary:- thyroid/parathyroid:- adrenal gland:457.10 pancreas:53.30 breast:120.80 salivary:-
GeneChip uterus:7.48 placenta:7.44 prostate:6.58 ovary:7.36 testis:6.27 heart:7.05 muscle:6.04 esophagus:6.74 stomach:7.46 intestine:7.04 colon:7.36 liver/hepato:6.90 lung:8 bladder:- kidney:7.05 pituitary:6.88 thyroid/parathyroid:7.16 adrenal gland:7.46 pancreas:6.47 breast:7.28 salivary:6.27
CAGE uterus:3.82 placenta:3.73 prostate:3.69 ovary:3.58 testis:3.47 heart:3.55 muscle:2.83 esophagus:3.71 stomach:- intestine:3.74 colon:3.64     liver/hepato:3.43    lung:4.27 bladder:4.17 kidney:3.65 pituitary:3.13 thyroid/parathyroid:3.23 adrenal gland:- pancreas:3.26 breast:3.78 salivary:2.63
RNA-seq uterus:- placenta:- prostate:4.41 ovary:3.64 testis:4.00 heart:2.65 muscle:2.02 esophagus:- stomach:- intestine:- colon:4.16     liver/hepato:2.74        lung:4.46    bladder:- kidney:3.35 pituitary:- thyroid/parathyroid:2.96 adrenal gland:5.30 pancreas:- breast:3.39 salivary:-

Gene Information

IDs

Refseq ID NM_005028
Gene ID 5305
Unigene ID Hs.570791
Probe set ID 212829_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000150867
GTEx ID ENSG00000150867

Orthologous Gene

Mouse[3]  NM_008845
Rat [0]  

Chromosomal Region

10p12.2  [22,823,778  -  23,003,503]

Gene Family (Interpro ID)

IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034  Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup

Link to Pubmed  (Pubmed ID)

7629060
7639683
7852364
8869744
9367159
12477932
12509423
14582145
14614850
14614854
14702039
15046600
15164054
15489334
16094259
16385451
16801950
16823801
17410640
17555944
18314871
18364242
18545987
19328558
19475563
19644675
19656170
19937977
20379614
20583997
21041608
21124964
21139048
21377334
21906983
21988832
22053931
22190034
22952844
23251661
23455922
23739505
23996088
24081551
24086693
24209622
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006661  phosphatidylinositol biosynthetic process
GO:0006644  phospholipid metabolic process
GO:0016310  phosphorylation

Cellular Component

GO:0005575  cellular_component
GO:0005829  cytosol
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0016308  1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016309  1-phosphatidylinositol-5-phosphate 4-kinase activity
GO:0005524  ATP binding