polycystic kidney disease 1 (autosomal dominant)

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Synonym

Polycystin-1 precursor, PKD1, polycystic kidney disease 1 (autosomal dominant)

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:65.20

cerebellum:352.60

brain stem:-

corpus callosum/glia:-

pineal gland:445

peripheral nerve:30.70

spine:-

retina:-

eye:152.80

artery/aorta:-

vein:-

lymphnode:50.60

peripheral blood:-

spleen:113.40

thymus:77.30

bone marrow:39.40

adipose:-

bone:25.60

skin:28.80

GeneChip

cerebrum:7.55

cerebellum:9.56

brain stem:7.12

corpus callosum/glia:7.47

pineal gland:-

peripheral nerve:7.32

spine:7.06

retina:-

eye:-

artery/aorta:7.99

vein:7.08

lymphnode:7.01

peripheral blood:-

spleen:6.87

thymus:6.88

bone marrow:6.35

adipose:7.11

bone:-

skin:7.20

CAGE

nodata

RNA-seq

cerebrum:1.83

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.49

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.34

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:36.40

prostate:-

ovary:149.10

testis:77.90

heart:25.50

muscle:20.10

esophagus:-

stomach:42.50

intestine:32.40

colon:59.40

liver/hepato:-

lung:68.40

bladder:-

kidney:72.80

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:97.80

breast:65.10

salivary:-

GeneChip

uterus:7.58

placenta:6.26

prostate:6.86

ovary:7.29

testis:7.19

heart:7.20

muscle:7.17

esophagus:7.04

stomach:7.09

intestine:6.85

colon:6.94

liver/hepato:6.90

lung:7.34

bladder:-

kidney:6.70

pituitary:8.69

thyroid/parathyroid:6.84

adrenal gland:7.08

pancreas:6.44

breast:7.66

salivary:6.92

CAGE

nodata

RNA-seq

uterus:-

placenta:-

prostate:2.80

ovary:2.29

testis:1.01

heart:2.08

muscle:2.59

esophagus:-

stomach:-

intestine:-

colon:0.55

liver/hepato:0.91

lung:1.47

bladder:-

kidney:0.60

pituitary:-

thyroid/parathyroid:1.22

adrenal gland:1.12

pancreas:-

breast:1.72

salivary:-

IDs

Refseq ID	NM_001009944
Gene ID	5310
Unigene ID	Hs.75813
Probe set ID	202328_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000008710
GTEx ID	ENSG00000008710

Orthologous Gene

Mouse[1]	NM_013630
Rat[1]	NM_013630

Chromosomal Region

16p13.3 [2,138,711 - 2,185,899]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001304	C-type lectin
IPR016187	C-type lectin fold
IPR016186	C-type lectin-like
IPR002889	Carbohydrate-binding WSC
IPR013994	Carbohydrate-binding WSC, subgroup
IPR014010	Egg jelly receptor, REJ-like
IPR008976	Lipase/lipooxygenase, PLAT/LH2
IPR001024	Lipoxygenase, LH2

Gene Ontology (GO ID)

Biological Process

GO:0009653	anatomical structure morphogenesis
GO:0048754	branching morphogenesis of a tube
GO:0070588	calcium ion transmembrane transport
GO:0007161	calcium-independent cell-matrix adhesion
GO:0001502	cartilage condensation
GO:0051216	cartilage development
GO:0007050	cell cycle arrest
GO:0007160	cell-matrix adhesion
GO:0042994	cytoplasmic sequestering of transcription factor
GO:0050982	detection of mechanical stimulus
GO:0001892	embryonic placenta development
GO:0048806	genitalia development
GO:0048565	gut development
GO:0007507	heart development
GO:0007156	homophilic cell adhesion
GO:0001701	in utero embryonic development
GO:0007259	JAK-STAT cascade
GO:0001822	kidney development
GO:0001889	liver development
GO:0060428	lung epithelium development
GO:0021915	neural tube development
GO:0007218	neuropeptide signaling pathway
GO:0006807	nitrogen compound metabolic process
GO:0018105	peptidyl-serine phosphorylation
GO:0060674	placenta blood vessel development
GO:0031659	positive regulation of cyclin-dependent protein kinase activity during G1/S
GO:0032092	positive regulation of protein binding
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006611	protein export from nucleus
GO:0060236	regulation of mitotic spindle organization
GO:0043588	skin development
GO:0021510	spinal cord development

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0005929	cilium
GO:0005737	cytoplasm
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0031512	motile primary cilium
GO:0005634	nucleus
GO:0002133	polycystin complex

Molecular Function

GO:0005262	calcium channel activity
GO:0030246	carbohydrate binding
GO:0005261	cation channel activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0019901	protein kinase binding

polycystic kidney disease 1 (autosomal dominant)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function