plectin 1, intermediate filament binding protein 500kDa

Synonym

EBS1, Plectin-1, PLTN, EBSO, PCN, Hemidesmosomal protein 1, PLEC1b, HD1, intermediate filament binding protein, epidermolysis bullosa simplex 1 (Ogna), PLEC1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:36.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:276

spine:1010.70

retina:-

eye:146.90

artery/aorta:-

vein:133.30

lymphnode:121.30

peripheral blood:18.20

spleen:113.40

thymus:25.80

bone marrow:157.40

adipose:-

bone:64

skin:81.60

GeneChip

cerebrum:7.51

cerebellum:7.78

brain stem:7.37

corpus callosum/glia:8.02

pineal gland:-

peripheral nerve:8.37

spine:7.98

retina:-

eye:-

artery/aorta:8.06

vein:7.82

lymphnode:7.82

peripheral blood:-

spleen:7.50

thymus:7.66

bone marrow:7.22

adipose:7.73

bone:-

skin:7.89

CAGE

cerebrum:4.11

cerebellum:-

brain stem:4.02

corpus callosum/glia:4.34

pineal gland:3.49

peripheral nerve:-

spine:4.13

retina:-

eye:-

artery/aorta:5.08

vein:4.48

lymphnode:4.52

peripheral blood:-

spleen:4.11

thymus:4.22

bone marrow:-

adipose:4.66

bone:-

skin:-

RNA-seq

cerebrum:0.34

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.89

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.34

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:98.40

prostate:56.30

ovary:186.30

testis:30.30

heart:89.40

muscle:221

esophagus:-

stomach:127.50

intestine:-

colon:407

liver/hepato:-

lung:83.10

bladder:-

kidney:20.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:115.60

breast:130.10

salivary:-

GeneChip

uterus:7.54

placenta:7.83

prostate:7.35

ovary:7.53

testis:6.95

heart:7.87

muscle:8.60

esophagus:8.58

stomach:7.66

intestine:7.68

colon:7.99

liver/hepato:7.55

lung:7.92

bladder:-

kidney:7.39

pituitary:7.48

thyroid/parathyroid:7.37

adrenal gland:7.64

pancreas:7.35

breast:8.06

salivary:7.87

CAGE

uterus:4.64

placenta:4.70

prostate:4.34

ovary:4.48

testis:3.76

heart:4.68

muscle:5.51

esophagus:4.82

stomach:-

intestine:4.76

colon:4.65

liver/hepato:3.70

lung:4.49

bladder:4.43

kidney:3.84

pituitary:3.24

thyroid/parathyroid:3.46

adrenal gland:-

pancreas:3.92

breast:4.03

salivary:4.34

RNA-seq

uterus:-

placenta:-

prostate:0.27

ovary:0.75

testis:0.53

heart:0.15

muscle:0.79

esophagus:-

stomach:-

intestine:-

colon:0.83

liver/hepato:0.07

lung:0.06

bladder:-

kidney:0.36

pituitary:-

thyroid/parathyroid:0.42

adrenal gland:0.94

pancreas:-

breast:0.36

salivary:-

IDs

Refseq ID	NM_201384
Gene ID	5339
Unigene ID	Hs.434248
Probe set ID	201373_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000178209
GTEx ID	ENSG00000178209

Orthologous Gene

Mouse[30]	NM_001163540, NM_001163542, NM_001163549, NM_001164203, NM_011117, NM_201385, NM_201386, NM_201387, NM_201388, NM_201389, NM_201390, NM_201391, NM_201392, NM_201393, NM_201394
Rat[13]	NM_001164296, NM_001164297, NM_001164298, NM_001164299, NM_001164302, NM_001164303, NM_001164304, NM_001164305, NM_001164307, NM_001164308, NM_022401, NM_201391, NM_201392, NM_201393, NM_201394

Chromosomal Region

8q24.3 [144,989,321 - 145,050,902]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016146	Calponin-homology
IPR001715	Calponin-like actin-binding
IPR018159	Spectrin/alpha-actinin

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0034329	cell junction assembly
GO:0006921	cell structure disassembly during apoptosis
GO:0030198	extracellular matrix organization
GO:0031581	hemidesmosome assembly

Cellular Component

GO:0043034	costamere
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0030056	hemidesmosome
GO:0045111	intermediate filament cytoskeleton
GO:0005886	plasma membrane
GO:0042383	sarcolemma
GO:0016528	sarcoplasm

Molecular Function

GO:0003779	actin binding
GO:0030506	ankyrin binding
GO:0005515	protein binding
GO:0008307	structural constituent of muscle

plectin 1, intermediate filament binding protein 500kDa

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function