polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

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Synonym

POLR2B, DNA-directed RNA polymerase II 140 kDa polypeptide, hsRPB2, hRPB140, RPB2, RNA polymerase II subunit 2, POL2RB

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:138.70

cerebellum:113.30

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:61.30

spine:112.30

retina:-

eye:88.20

artery/aorta:299.80

vein:-

lymphnode:111.20

peripheral blood:-

spleen:37.80

thymus:231.90

bone marrow:39.40

adipose:-

bone:38.40

skin:96

GeneChip

cerebrum:8.31

cerebellum:8.80

brain stem:8.43

corpus callosum/glia:8.21

pineal gland:-

peripheral nerve:8.27

spine:8.10

retina:-

eye:-

artery/aorta:8.07

vein:8.38

lymphnode:8.62

peripheral blood:-

spleen:8.69

thymus:9.29

bone marrow:8.16

adipose:8.30

bone:-

skin:8.34

CAGE

cerebrum:4.42

cerebellum:-

brain stem:4.35

corpus callosum/glia:3.98

pineal gland:4.59

peripheral nerve:-

spine:4.47

retina:-

eye:-

artery/aorta:3.94

vein:3.95

lymphnode:4.22

peripheral blood:-

spleen:4.20

thymus:4.32

bone marrow:-

adipose:4.13

bone:-

skin:-

RNA-seq

cerebrum:4.55

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.52

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.08

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:164

placenta:105.60

prostate:78.90

ovary:37.30

testis:190.40

heart:127.70

muscle:20.10

esophagus:-

stomach:169.90

intestine:129.60

colon:152.60

liver/hepato:42.20

lung:195.50

bladder:125.60

kidney:114.40

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:50.80

pancreas:88.90

breast:83.60

salivary:-

GeneChip

uterus:8.76

placenta:8.44

prostate:8.67

ovary:8.94

testis:8.66

heart:8.47

muscle:9.07

esophagus:8.40

stomach:8.36

intestine:8.52

colon:8.20

liver/hepato:7.94

lung:8.31

bladder:-

kidney:8.09

pituitary:8.41

thyroid/parathyroid:8.52

adrenal gland:8.28

pancreas:8.18

breast:8.48

salivary:8.21

CAGE

uterus:4.25

placenta:4.16

prostate:3.97

ovary:3.95

testis:4.25

heart:4.49

muscle:4.45

esophagus:4.06

stomach:-

intestine:4.17

colon:4.05

liver/hepato:3.80

lung:3.96

bladder:4.09

kidney:4.11

pituitary:4.65

thyroid/parathyroid:3.89

adrenal gland:-

pancreas:4.19

breast:3.60

salivary:4.16

RNA-seq

uterus:-

placenta:-

prostate:4.69

ovary:4.73

testis:5.09

heart:4.50

muscle:4.72

esophagus:-

stomach:-

intestine:-

colon:4.26

liver/hepato:3.66

lung:3.87

bladder:-

kidney:4.53

pituitary:-

thyroid/parathyroid:5.25

adrenal gland:5.00

pancreas:-

breast:4.30

salivary:-

IDs

Refseq ID	NM_000938
Gene ID	5431
Unigene ID	Hs.602757
Probe set ID	201803_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000047315
GTEx ID	ENSG00000047315

Orthologous Gene

Mouse[1]	NM_153798
Rat[1]	NM_001106002

Chromosomal Region

4q12 [57,843,888 - 57,897,334]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006281	DNA repair
GO:0010467	gene expression
GO:0006370	mRNA capping
GO:0000398	nuclear mRNA splicing, via spliceosome
GO:0006289	nucleotide-excision repair
GO:0050434	positive regulation of viral transcription
GO:0006368	RNA elongation from RNA polymerase II promoter
GO:0008380	RNA splicing
GO:0006366	transcription from RNA polymerase II promoter
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006283	transcription-coupled nucleotide-excision repair
GO:0016032	viral reproduction

Cellular Component

GO:0005665	DNA-directed RNA polymerase II, core complex
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0003899	DNA-directed RNA polymerase activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0032549	ribonucleoside binding

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function