DnaJ (Hsp40) homolog, subfamily C, member 10

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Synonym

JPDI, DKFZp434J1813, ERdj5, DNAJC10, MGC104194, DnaJ (Hsp40) homolog, subfamily C, member 10

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83 cerebellum:25.20 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:92 spine:112.30 retina:- eye:41.10 artery/aorta:359.70 vein:199.90 lymphnode:161.80 peripheral blood:36.40 spleen:113.40 thymus:128.80 bone marrow:19.70 adipose:- bone:51.20 skin:38.40
GeneChip cerebrum:4.26 cerebellum:3.80 brain stem:4.62 corpus callosum/glia:4.47 pineal gland:- peripheral nerve:4.78 spine:4.53 retina:- eye:- artery/aorta:5.02 vein:4.43 lymphnode:5.27 peripheral blood:- spleen:5.06 thymus:5.47 bone marrow:4.05 adipose:4.50 bone:- skin:4.57
CAGE cerebrum:4.01 cerebellum:- brain stem:4.14 corpus callosum/glia:3.91 pineal gland:4.62 peripheral nerve:- spine:4.36 retina:- eye:- artery/aorta:4.62 vein:4.48 lymphnode:4.50 peripheral blood:- spleen:4.56 thymus:4.23 bone marrow:- adipose:3.96 bone:- skin:-
RNA-seq cerebrum:3.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.22 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:127.60 placenta:40.10 prostate:45.10 ovary:74.50 testis:337.50 heart:38.30 muscle:- esophagus:- stomach:127.50 intestine:64.80 colon:50.90     liver/hepato:52.80        lung:249.30    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:327.50 adrenal gland:50.80 pancreas:106.70 breast:9.30 salivary:-
GeneChip uterus:5.93 placenta:4.57 prostate:5.88 ovary:5.14 testis:6.26 heart:4.63 muscle:3.95 esophagus:4.16 stomach:5.37 intestine:5.34 colon:4.08 liver/hepato:4.78 lung:4.52 bladder:- kidney:4.10 pituitary:5.26 thyroid/parathyroid:4.73 adrenal gland:4.24 pancreas:5.62 breast:4.65 salivary:4.89
CAGE uterus:4.49 placenta:3.93 prostate:4.27 ovary:4.46 testis:4.42 heart:4.62 muscle:3.79 esophagus:3.95 stomach:- intestine:3.99 colon:4.15     liver/hepato:4.26    lung:4.51 bladder:4.20 kidney:4.44 pituitary:4.77 thyroid/parathyroid:4.36 adrenal gland:- pancreas:4.58 breast:4.53 salivary:4.34
RNA-seq uterus:- placenta:- prostate:4.37 ovary:4.96 testis:5.05 heart:3.87 muscle:2.92 esophagus:- stomach:- intestine:- colon:4.21     liver/hepato:3.90        lung:4.12    bladder:- kidney:4.81 pituitary:- thyroid/parathyroid:4.75 adrenal gland:4.54 pancreas:- breast:4.16 salivary:-

Gene Information

IDs

Refseq ID NM_018981
Gene ID 54431
Unigene ID Hs.516632
Probe set ID 221782_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000077232
GTEx ID ENSG00000077232

Orthologous Gene

Mouse[3]  NM_024181
Rat [0]  

Chromosomal Region

2q32.1  [183,580,999  -  183,653,542]

Gene Family (Interpro ID)

IPR003095  Heat shock protein DnaJ
IPR015609  Molecular chaperone, heat shock protein, Hsp40, DnaJ

Link to Pubmed  (Pubmed ID)

12411443
12446677
12477932
12975309
14587667
14702039
15489334
15815621
16189514
16303743
16344560
17353921
18400946
18653895
19122239
19706418
19815549
19946888
20347046
21139048
21145461
21266254
21329881
21632540
21890473
21906983
22229892
22354994
22797925
23192594
23363602
23769672
23973329
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0045454  cell redox homeostasis
GO:0030433  ER-associated protein catabolic process
GO:0006662  glycerol ether metabolic process
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0032781  positive regulation of ATPase activity
GO:0034975  protein folding in endoplasmic reticulum
GO:0034976  response to endoplasmic reticulum stress

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0034663  endoplasmic reticulum chaperone complex
GO:0005788  endoplasmic reticulum lumen
GO:0005576  extracellular region

Molecular Function

GO:0001671  ATPase activator activity
GO:0051117  ATPase binding
GO:0051087  chaperone binding
GO:0015036  disulfide oxidoreductase activity
GO:0009055  electron carrier activity
GO:0030544  Hsp70 protein binding
GO:0051787  misfolded protein binding
GO:0016671  oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor
GO:0005515  protein binding
GO:0015035  protein disulfide oxidoreductase activity