Ras and Rab interactor 2

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Synonym

Ras interaction/interference protein 2, Ras association domain family 4, Ras and Rab interactor 2, RASSF4, Ras inhibitor JC265, RIN2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26.10 cerebellum:- brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:184 spine:- retina:355.90 eye:52.90 artery/aorta:89.90 vein:66.60 lymphnode:10.10 peripheral blood:18.20 spleen:75.60 thymus:- bone marrow:- adipose:40.30 bone:89.60 skin:57.60
GeneChip cerebrum:7.18 cerebellum:5.62 brain stem:7.27 corpus callosum/glia:8 pineal gland:- peripheral nerve:6.89 spine:8.05 retina:- eye:- artery/aorta:7.53 vein:7.60 lymphnode:6.79 peripheral blood:- spleen:8.23 thymus:5.64 bone marrow:5.01 adipose:7.79 bone:- skin:8.23
CAGE cerebrum:3.40 cerebellum:- brain stem:3.66 corpus callosum/glia:4.13 pineal gland:3.36 peripheral nerve:- spine:3.55 retina:- eye:- artery/aorta:3.64 vein:2.92 lymphnode:2.98 peripheral blood:- spleen:3.56 thymus:1.22 bone marrow:- adipose:4.24 bone:- skin:-
RNA-seq cerebrum:3.44 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.33 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.97 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:40.10 prostate:90.10 ovary:37.30 testis:8.70 heart:12.80 muscle:20.10 esophagus:- stomach:- intestine:64.80 colon:144.20     liver/hepato:21.10        lung:44    bladder:- kidney:114.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:102.20 salivary:-
GeneChip uterus:8.16 placenta:7.82 prostate:8.38 ovary:8.22 testis:5 heart:8.13 muscle:6.72 esophagus:7.63 stomach:7.37 intestine:7.52 colon:7.31 liver/hepato:6.33 lung:8.86 bladder:- kidney:7.98 pituitary:6.80 thyroid/parathyroid:8.10 adrenal gland:7.40 pancreas:7.35 breast:8.25 salivary:8.58
CAGE uterus:3.69 placenta:3.79 prostate:3.68 ovary:2.84 testis:2.60 heart:3.89 muscle:3.19 esophagus:3.67 stomach:- intestine:3.69 colon:3.37     liver/hepato:2.39    lung:4.35 bladder:3.50 kidney:3.63 pituitary:2.71 thyroid/parathyroid:3.28 adrenal gland:- pancreas:3.45 breast:4.18 salivary:4.06
RNA-seq uterus:- placenta:- prostate:3.92 ovary:3.45 testis:2.93 heart:3.02 muscle:2.59 esophagus:- stomach:- intestine:- colon:3.18     liver/hepato:2.00        lung:4.21    bladder:- kidney:3.49 pituitary:- thyroid/parathyroid:3.48 adrenal gland:3.35 pancreas:- breast:3.82 salivary:-

Gene Information

IDs

Refseq ID NM_018993
Gene ID 54453
Unigene ID Hs.472270
Probe set ID 209684_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000132669
GTEx ID ENSG00000132669

Orthologous Gene

Mouse[2]  NM_028724
Rat[1]  NM_001107786

Chromosomal Region

20p11.23  [19,867,165  -  19,983,101]

Gene Family (Interpro ID)

IPR003123  Vacuolar sorting protein 9
IPR013995  Vacuolar sorting protein 9, subgroup

Link to Pubmed  (Pubmed ID)

1849280
8889548
11230166
11733506
11780052
12477932
12972505
14702039
16273093
16423831
17955473
19322201
19631308
20424861
20889312
21963094
23251661

Gene Ontology  (GO ID)

Biological Process

GO:0006897  endocytosis
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm

Molecular Function

GO:0005096  GTPase activator activity
GO:0017112  Rab guanyl-nucleotide exchange factor activity
GO:0005083  small GTPase regulator activity