P450 (cytochrome) oxidoreductase

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Synonym

P450R, DKFZp686G04235, POR, CPR, P450 (cytochrome) oxidoreductase, NADPH--cytochrome P450 reductase, FLJ26468, CYPOR

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:156.40

cerebellum:63

brain stem:-

corpus callosum/glia:29.20

pineal gland:148.30

peripheral nerve:92

spine:112.30

retina:118.60

eye:82.30

artery/aorta:60

vein:-

lymphnode:131.40

peripheral blood:327.90

spleen:132.30

thymus:206.10

bone marrow:39.40

adipose:80.70

bone:25.60

skin:100.80

GeneChip

cerebrum:6.18

cerebellum:5.86

brain stem:6.04

corpus callosum/glia:6.21

pineal gland:-

peripheral nerve:6.36

spine:6.19

retina:-

eye:-

artery/aorta:6.77

vein:6.35

lymphnode:6.72

peripheral blood:-

spleen:6.75

thymus:7.15

bone marrow:5.85

adipose:6.97

bone:-

skin:7.20

CAGE

cerebrum:2.54

cerebellum:-

brain stem:2.19

corpus callosum/glia:2.62

pineal gland:2.49

peripheral nerve:-

spine:2.06

retina:-

eye:-

artery/aorta:2.45

vein:2.51

lymphnode:2.56

peripheral blood:-

spleen:2.47

thymus:2.31

bone marrow:-

adipose:2.71

bone:-

skin:-

RNA-seq

cerebrum:3.02

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.91

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.55

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:118.50

placenta:185.80

prostate:202.80

ovary:298.10

testis:77.90

heart:51.10

muscle:20.10

esophagus:-

stomach:169.90

intestine:129.60

colon:118.70

liver/hepato:105.60

lung:112.40

bladder:376.80

kidney:52

pituitary:-

thyroid/parathyroid:327.50

adrenal gland:812.60

pancreas:97.80

breast:111.50

salivary:-

GeneChip

uterus:6.40

placenta:8.41

prostate:6.98

ovary:7.20

testis:6.96

heart:6.21

muscle:5.69

esophagus:7.27

stomach:6.32

intestine:6.66

colon:6.66

liver/hepato:9.56

lung:7.75

bladder:-

kidney:7.30

pituitary:7.46

thyroid/parathyroid:8.61

adrenal gland:9.17

pancreas:6.65

breast:6.91

salivary:5.86

CAGE

uterus:2.55

placenta:3.13

prostate:2.70

ovary:2.62

testis:3.39

heart:2.58

muscle:2.27

esophagus:2.24

stomach:-

intestine:3.55

colon:2.72

liver/hepato:4.19

lung:2.68

bladder:2.42

kidney:2.67

pituitary:3.32

thyroid/parathyroid:3.01

adrenal gland:-

pancreas:2.86

breast:3.06

salivary:2.22

RNA-seq

uterus:-

placenta:-

prostate:4.48

ovary:4.99

testis:4.76

heart:2.75

muscle:3.81

esophagus:-

stomach:-

intestine:-

colon:3.35

liver/hepato:7.36

lung:4.73

bladder:-

kidney:5.23

pituitary:-

thyroid/parathyroid:5.32

adrenal gland:3.97

pancreas:-

breast:4.78

salivary:-

IDs

Refseq ID	NM_000941
Gene ID	5447
Unigene ID	Hs.354056
Probe set ID	208928_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000127948
GTEx ID	ENSG00000127948

Orthologous Gene

Mouse[1]	NM_008898
Rat [0]

Chromosomal Region

7q11.23 [75,528,518 - 75,616,173]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001094	Flavodoxin-like
IPR008254	Flavodoxin/nitric oxide synthase
IPR001709	Flavoprotein pyridine nucleotide cytochrome reductase

Gene Ontology (GO ID)

Biological Process

GO:0009437	carnitine metabolic process
GO:0071372	cellular response to follicle-stimulating hormone stimulus
GO:0071375	cellular response to peptide hormone stimulus
GO:0070988	demethylation
GO:0019395	fatty acid oxidation
GO:0009812	flavonoid metabolic process
GO:0018393	internal peptidyl-lysine acetylation
GO:0043066	negative regulation of apoptosis
GO:0043154	negative regulation of caspase activity
GO:0060192	negative regulation of lipase activity
GO:0043602	nitrate catabolic process
GO:0046210	nitric oxide catabolic process
GO:0055114	oxidation reduction
GO:0045542	positive regulation of cholesterol biosynthetic process
GO:0032332	positive regulation of chondrocyte differentiation
GO:0032770	positive regulation of monooxygenase activity
GO:0045880	positive regulation of smoothened signaling pathway
GO:0090031	positive regulation of steroid hormone biosynthetic process
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation
GO:0042493	response to drug
GO:0007584	response to nutrient

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0005739	mitochondrion

Molecular Function

GO:0004128	cytochrome-b5 reductase activity
GO:0009055	electron carrier activity
GO:0019899	enzyme binding
GO:0050660	FAD binding
GO:0010181	FMN binding
GO:0016787	hydrolase activity
GO:0005506	iron ion binding
GO:0047726	iron-cytochrome-c reductase activity
GO:0050661	NADP or NADPH binding
GO:0003958	NADPH-hemoprotein reductase activity
GO:0005515	protein binding

P450 (cytochrome) oxidoreductase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function