DNA-damage-inducible transcript 4

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Synonym

RTP801, FLJ20500, RP11-442H21.1, DDIT4, Dig2, REDD-1, REDD1, DNA-damage-inducible transcript 4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:104.30 cerebellum:138.50 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:153.40 spine:112.30 retina:- eye:335 artery/aorta:30 vein:466.50 lymphnode:171.90 peripheral blood:182.20 spleen:- thymus:180.40 bone marrow:59 adipose:242 bone:319.90 skin:129.60
GeneChip cerebrum:7.69 cerebellum:8.23 brain stem:7.63 corpus callosum/glia:8.16 pineal gland:- peripheral nerve:9.84 spine:8.87 retina:- eye:- artery/aorta:8.89 vein:10.02 lymphnode:9.32 peripheral blood:- spleen:8.91 thymus:9.17 bone marrow:8.88 adipose:9.11 bone:- skin:8.81
CAGE cerebrum:3.15 cerebellum:- brain stem:3.56 corpus callosum/glia:2.69 pineal gland:2.56 peripheral nerve:- spine:3.77 retina:- eye:- artery/aorta:4.59 vein:3.67 lymphnode:3.82 peripheral blood:- spleen:3.29 thymus:4.04 bone marrow:- adipose:4.06 bone:- skin:-
RNA-seq cerebrum:4.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.63 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.63 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:109.40 placenta:87.40 prostate:56.30 ovary:37.30 testis:26 heart:38.30 muscle:140.60 esophagus:342.80 stomach:63.70 intestine:97.20 colon:93.30     liver/hepato:52.80        lung:127.10    bladder:1256.10 kidney:83.20 pituitary:- thyroid/parathyroid:- adrenal gland:507.90 pancreas:106.70 breast:65.10 salivary:-
GeneChip uterus:8.37 placenta:7.51 prostate:7.74 ovary:8.60 testis:7.51 heart:8.64 muscle:7.94 esophagus:10.12 stomach:8.17 intestine:8.91 colon:8.23 liver/hepato:8.07 lung:9.42 bladder:- kidney:8.70 pituitary:8.33 thyroid/parathyroid:7.89 adrenal gland:9.87 pancreas:10.79 breast:8.55 salivary:8.33
CAGE uterus:2.93 placenta:2.58 prostate:3.60 ovary:4.73 testis:2.83 heart:3.47 muscle:4.07 esophagus:4.38 stomach:- intestine:2.71 colon:3.62     liver/hepato:3.43    lung:4.24 bladder:4.42 kidney:2.86 pituitary:2.99 thyroid/parathyroid:3.34 adrenal gland:- pancreas:4.63 breast:5.31 salivary:2.95
RNA-seq uterus:- placenta:- prostate:6.95 ovary:7.86 testis:5.00 heart:4.80 muscle:6.52 esophagus:- stomach:- intestine:- colon:6.56     liver/hepato:4.32        lung:6.50    bladder:- kidney:5.58 pituitary:- thyroid/parathyroid:6.13 adrenal gland:6.45 pancreas:- breast:4.44 salivary:-

Gene Information

IDs

Refseq ID NM_019058
Gene ID 54541
Unigene ID Hs.523012
Probe set ID 202887_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000168209
GTEx ID ENSG00000168209

Orthologous Gene

Mouse[1]  NM_029083
Rat[1]  NM_080906

Chromosomal Region

10q22.1  [74,033,678  -  74,035,794]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11076863
11230166
11256614
11884613
12453409
12477932
14646594
15146197
15180327
15489336
15592522
15632201
15988001
16169070
16196087
16258273
16341674
16381901
16713569
17005863
17307335
18029348
18781797
18796435
18953439
19114033
19127203
19210572
19221489
19557001
19996311
20166753
20354178
20374513
20473305
20639865
20972266
21123297
21139048
21258409
21266827
21414293
21460850
21540236
21798997
21890473
21900206
21906983
21909097
21963094
21987572
22053931
22505724
22527987
23000965
23193052
23528835
23717519
24728411

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0008283  cell proliferation
GO:0051607  defense response to virus
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0045820  negative regulation of glycolysis
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0010801  negative regulation of peptidyl-threonine phosphorylation
GO:0010741  negative regulation of protein kinase cascade
GO:0032007  negative regulation of TOR signaling pathway
GO:0048011  nerve growth factor receptor signaling pathway
GO:0030182  neuron differentiation
GO:0001764  neuron migration
GO:0043241  protein complex disassembly
GO:0001666  response to hypoxia

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005622  intracellular
GO:0005739  mitochondrion