POU class 4 homeobox 1

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Synonym

Oct-T1, BRN3A, Homeobox/POU domain protein RDC-1, FLJ13449, POU4F1, Brain-specific homeobox/POU domain protein 3A, POU domain, class 4, transcription factor 1, Brn-3A, RDC-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.44 cerebellum:3.72 brain stem:3.42 corpus callosum/glia:3.31 pineal gland:- peripheral nerve:5.62 spine:3.80 retina:- eye:- artery/aorta:3.26 vein:3.65 lymphnode:3.29 peripheral blood:- spleen:3.23 thymus:3.57 bone marrow:3.59 adipose:3.24 bone:- skin:3.35
CAGE cerebrum:0.10 cerebellum:- brain stem:0.30 corpus callosum/glia:0.07 pineal gland:0 peripheral nerve:- spine:1.06 retina:- eye:- artery/aorta:1.10 vein:0.47 lymphnode:0.35 peripheral blood:- spleen:0.09 thymus:0.96 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.05 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:3.28 placenta:4.17 prostate:3.15 ovary:3.43 testis:3.35 heart:3.19 muscle:3.53 esophagus:3.14 stomach:3.25 intestine:3.45 colon:3.44 liver/hepato:3.24 lung:3.41 bladder:- kidney:3.21 pituitary:3.06 thyroid/parathyroid:3.04 adrenal gland:2.96 pancreas:3.65 breast:3.30 salivary:3.19
CAGE uterus:0 placenta:0.16 prostate:0 ovary:0 testis:1.19 heart:0 muscle:0.17 esophagus:0 stomach:- intestine:0 colon:0.04     liver/hepato:0.14    lung:0.05 bladder:0.18 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0.55 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:1.02 heart:0.02 muscle:0.08 esophagus:- stomach:- intestine:- colon:0.03     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.01 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_006237
Gene ID 5457
Unigene ID -
Probe set ID 211341_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000152192
GTEx ID ENSG00000152192

Orthologous Gene

Mouse[1]  NM_011143
Rat[1]  NM_011143

Chromosomal Region

13q31.1  [79,173,227  -  79,177,695]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

1357630
7623109
8234287
8248179
8889548
8941380
8995448
9448000
12427558
12432261
12441296
12477932
12810599
12893201
12911730
12934100
15021903
15272315
16247485
16276351
17239249
20348952
20376082
21116278
21928122
22064348
22930747
23666755

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0021535  cell migration in hindbrain
GO:0021953  central nervous system neuron differentiation
GO:0021986  habenula development
GO:0060384  innervation
GO:0007498  mesoderm development
GO:0043524  negative regulation of neuron apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048665  neuron fate specification
GO:0048935  peripheral nervous system neuron development
GO:0043065  positive regulation of apoptosis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0051355  proprioception during equilibrioception
GO:0050767  regulation of neurogenesis
GO:0048880  sensory system development
GO:0001967  suckling behavior
GO:0007416  synapse assembly
GO:0021559  trigeminal nerve development
GO:0003223  ventricular compact myocardium morphogenesis

Cellular Component

GO:0043005  neuron projection
GO:0000790  nuclear chromatin

Molecular Function

GO:0003705  RNA polymerase II transcription factor activity, enhancer binding