alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)

Synonym

SHS, XNP, ATP-dependent helicase ATRX, MRXS3, ZNF-HX, Transcriptional regulator ATRX, RAD54L, ATRX, Znf-HX, X-linked helicase II, XH2, X-linked nuclear protein, ATR2, MGC2094, RAD54

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:7.46

cerebellum:8.26

brain stem:7.21

corpus callosum/glia:7.19

pineal gland:-

peripheral nerve:7.09

spine:7.26

retina:-

eye:-

artery/aorta:7.10

vein:7.07

lymphnode:7.31

peripheral blood:-

spleen:7.51

thymus:7.96

bone marrow:6.45

adipose:7.22

bone:-

skin:6.82

CAGE

cerebrum:4.09

cerebellum:-

brain stem:4.16

corpus callosum/glia:3.18

pineal gland:4.56

peripheral nerve:-

spine:4.17

retina:-

eye:-

artery/aorta:3.52

vein:3.64

lymphnode:3.53

peripheral blood:-

spleen:4.03

thymus:4.10

bone marrow:-

adipose:3.85

bone:-

skin:-

RNA-seq

cerebrum:3.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.23

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:7.61

placenta:6.58

prostate:7.67

ovary:7.51

testis:5.52

heart:7.27

muscle:7.31

esophagus:6.56

stomach:7.02

intestine:6.95

colon:5.60

liver/hepato:6.19

lung:7.07

bladder:-

kidney:6.76

pituitary:7.59

thyroid/parathyroid:7.38

adrenal gland:7.19

pancreas:6.24

breast:7.13

salivary:6.84

CAGE

uterus:3.67

placenta:3.41

prostate:4.10

ovary:4.02

testis:2.92

heart:3.99

muscle:3.64

esophagus:3.76

stomach:-

intestine:3.43

colon:3.51

liver/hepato:3.02

lung:3.88

bladder:4.10

kidney:3.69

pituitary:4.36

thyroid/parathyroid:3.56

adrenal gland:-

pancreas:2.60

breast:3.86

salivary:2.39

RNA-seq

uterus:-

placenta:-

prostate:2.87

ovary:3.15

testis:2.11

heart:2.42

muscle:2.63

esophagus:-

stomach:-

intestine:-

colon:2.81

liver/hepato:1.51

lung:2.28

bladder:-

kidney:3.21

pituitary:-

thyroid/parathyroid:2.51

adrenal gland:2.31

pancreas:-

breast:2.76

salivary:-

IDs

Refseq ID	NM_138270
Gene ID	546
Unigene ID	-
Probe set ID	208861_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000085224
GTEx ID	ENSG00000085224

Orthologous Gene

Mouse[5]	NM_009530
Rat[5]	NM_009530

Chromosomal Region

Xq21.1 [76,760,378 - 77,041,702]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR014001	DEAD-like helicase, N-terminal
IPR014021	Helicase, superfamily 1/2, ATP-binding domain

Gene Ontology (GO ID)

Biological Process

GO:0032508	DNA duplex unwinding
GO:0006306	DNA methylation
GO:0006310	DNA recombination
GO:0006281	DNA repair
GO:0030900	forebrain development
GO:0006355	regulation of transcription, DNA-dependent

Cellular Component

GO:0005720	nuclear heterochromatin
GO:0005634	nucleus

Molecular Function

GO:0005524	ATP binding
GO:0003682	chromatin binding
GO:0070087	chromo shadow domain binding
GO:0003677	DNA binding
GO:0003678	DNA helicase activity
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function