membrane-associated ring finger (C3HC4) 5

 jump to detail

Synonym

MARCH-V, FLJ20445, RNF153, MARCH5, ring finger protein 153, membrane-associated ring finger (C3HC4) 5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:73.50 cerebellum:88.20 brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:61.30 spine:- retina:237.30 eye:47 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:54.70 spleen:56.70 thymus:747.30 bone marrow:118.10 adipose:40.30 bone:64 skin:48
GeneChip cerebrum:5.93 cerebellum:6.13 brain stem:6.03 corpus callosum/glia:5.92 pineal gland:- peripheral nerve:6.33 spine:6.16 retina:- eye:- artery/aorta:5.97 vein:6.27 lymphnode:6.32 peripheral blood:- spleen:6.18 thymus:7.19 bone marrow:6.41 adipose:6.59 bone:- skin:6.32
CAGE cerebrum:3.43 cerebellum:- brain stem:3.34 corpus callosum/glia:3.22 pineal gland:3.41 peripheral nerve:- spine:3.34 retina:- eye:- artery/aorta:3.56 vein:3.63 lymphnode:3.45 peripheral blood:- spleen:3.07 thymus:3.65 bone marrow:- adipose:3.54 bone:- skin:-
RNA-seq cerebrum:3.71 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.46 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:69.20 prostate:67.60 ovary:74.50 testis:56.20 heart:- muscle:40.20 esophagus:342.80 stomach:21.20 intestine:- colon:25.40     liver/hepato:10.60        lung:73.30    bladder:125.60 kidney:- pituitary:579.90 thyroid/parathyroid:- adrenal gland:50.80 pancreas:44.50 breast:37.20 salivary:-
GeneChip uterus:6.63 placenta:6.94 prostate:6.94 ovary:6.73 testis:7.04 heart:6.53 muscle:6.44 esophagus:7.66 stomach:6.30 intestine:6.52 colon:6.26 liver/hepato:6.36 lung:6.10 bladder:- kidney:6.63 pituitary:5.83 thyroid/parathyroid:6.67 adrenal gland:6.46 pancreas:6.06 breast:6.62 salivary:6.89
CAGE uterus:3.32 placenta:3.36 prostate:3.28 ovary:3.43 testis:3.54 heart:3.74 muscle:3.99 esophagus:3.68 stomach:- intestine:3.37 colon:3.46     liver/hepato:3.44    lung:3.61 bladder:3.34 kidney:3.40 pituitary:3.25 thyroid/parathyroid:3.46 adrenal gland:- pancreas:3.37 breast:3.96 salivary:3.37
RNA-seq uterus:- placenta:- prostate:3.59 ovary:4.05 testis:3.80 heart:3.26 muscle:2.95 esophagus:- stomach:- intestine:- colon:3.14     liver/hepato:3.15        lung:3.38    bladder:- kidney:3.81 pituitary:- thyroid/parathyroid:4.07 adrenal gland:3.42 pancreas:- breast:4.18 salivary:-

Gene Information

IDs

Refseq ID NM_017824
Gene ID 54708
Unigene ID Hs.573490
Probe set ID 218582_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198060
GTEx ID ENSG00000198060

Orthologous Gene

Mouse[10]  NM_001164336, NM_001164337, NM_027314
Rat [0]  

Chromosomal Region

10q23.32  [94,050,920  -  94,113,721]

Gene Family (Interpro ID)

IPR018957  Zinc finger, C3HC4 RING-type
IPR011016  Zinc finger, RING-CH-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

12477932
14702039
14722266
15164054
15489334
16874301
16936636
17606867
18781797
19549727
19741096
19946888
20103533
20682791
20851218
21139048
21625535
21890473
21906983
21987572
22308378
22505724
23253261
23503661
23727017
24722297

Gene Ontology  (GO ID)

Biological Process

GO:0090141  positive regulation of mitochondrial fission
GO:0051865  protein autoubiquitination
GO:0070585  protein localization in mitochondrion
GO:0000209  protein polyubiquitination
GO:0090140  regulation of mitochondrial fission

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0005741  mitochondrial outer membrane

Molecular Function

GO:0051020  GTPase binding
GO:0005515  protein binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding