peptidylprolyl isomerase C (cyclophilin C)

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Synonym

PPIC, MGC3673, Cyclophilin C, CYPC, peptidylprolyl isomerase C (cyclophilin C), Peptidyl-prolyl cis-trans isomerase C

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:11.80 artery/aorta:- vein:66.60 lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:4.80
GeneChip cerebrum:4.94 cerebellum:4.52 brain stem:5.06 corpus callosum/glia:5.31 pineal gland:- peripheral nerve:6.61 spine:5.65 retina:- eye:- artery/aorta:8.14 vein:8.67 lymphnode:6.48 peripheral blood:- spleen:5.95 thymus:5.53 bone marrow:4.98 adipose:7.96 bone:- skin:7.49
CAGE cerebrum:1.85 cerebellum:- brain stem:2.14 corpus callosum/glia:2.14 pineal gland:3.50 peripheral nerve:- spine:2.72 retina:- eye:- artery/aorta:4.53 vein:3.40 lymphnode:3.14 peripheral blood:- spleen:2.96 thymus:1.58 bone marrow:- adipose:3.86 bone:- skin:-
RNA-seq cerebrum:1.17 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.39 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.88 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:32.80 prostate:22.50 ovary:- testis:26 heart:12.80 muscle:20.10 esophagus:- stomach:63.70 intestine:- colon:8.50     liver/hepato:-        lung:44    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:106.70 breast:37.20 salivary:-
GeneChip uterus:8.40 placenta:7.74 prostate:7.67 ovary:7.46 testis:6.25 heart:8.17 muscle:8.15 esophagus:8.68 stomach:7.76 intestine:8.19 colon:8.38 liver/hepato:7.12 lung:7.49 bladder:- kidney:7.57 pituitary:5.31 thyroid/parathyroid:8.72 adrenal gland:7.38 pancreas:7.29 breast:7.76 salivary:8
CAGE uterus:3.94 placenta:3.97 prostate:3.71 ovary:3.34 testis:2.94 heart:4.34 muscle:3.61 esophagus:4.29 stomach:- intestine:4.20 colon:4.37     liver/hepato:3.71    lung:3.59 bladder:4.16 kidney:3.96 pituitary:2.77 thyroid/parathyroid:4.37 adrenal gland:- pancreas:3.84 breast:4.18 salivary:3.87
RNA-seq uterus:- placenta:- prostate:4.94 ovary:4.25 testis:4.76 heart:4.26 muscle:3.66 esophagus:- stomach:- intestine:- colon:4.91     liver/hepato:3.95        lung:4.47    bladder:- kidney:4.85 pituitary:- thyroid/parathyroid:5.35 adrenal gland:4.93 pancreas:- breast:5.14 salivary:-

Gene Information

IDs

Refseq ID NM_000943
Gene ID 5480
Unigene ID Hs.110364
Probe set ID 204517_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000168938
GTEx ID ENSG00000168938

Orthologous Gene

Mouse[1]  NM_008908
Rat[1]  NM_001004215

Chromosomal Region

5q23.2  [122,358,945  -  122,372,436]

Gene Family (Interpro ID)

IPR015891  Cyclophilin-like
IPR002130  Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Link to Pubmed  (Pubmed ID)

1383094
1652374
7909608
8031755
8341703
9045699
10077627
12477932
15489334
16713569
17207965
19322201
19584346
21139048
21988832
22939629

Gene Ontology  (GO ID)

Biological Process

GO:0006457  protein folding
GO:0007165  signal transduction

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0016018  cyclosporin A binding
GO:0003755  peptidyl-prolyl cis-trans isomerase activity
GO:0051082  unfolded protein binding