protein phosphatase 1, catalytic subunit, alpha isoform

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Synonym

PP-1A, PPP1CA, MGC1674, PPP1A, MGC15877

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:86.50

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:148.30

peripheral nerve:61.30

spine:-

retina:-

eye:135.20

artery/aorta:89.90

vein:66.60

lymphnode:384.20

peripheral blood:218.60

spleen:56.70

thymus:90.20

bone marrow:177.10

adipose:121

bone:51.20

skin:67.20

GeneChip

cerebrum:7.54

cerebellum:7.32

brain stem:7.49

corpus callosum/glia:7.50

pineal gland:-

peripheral nerve:7.56

spine:7.34

retina:-

eye:-

artery/aorta:7.57

vein:7.16

lymphnode:8.65

peripheral blood:-

spleen:8.51

thymus:9.16

bone marrow:8.62

adipose:7.81

bone:-

skin:8.49

CAGE

cerebrum:3.92

cerebellum:-

brain stem:3.82

corpus callosum/glia:4.03

pineal gland:3.64

peripheral nerve:-

spine:3.55

retina:-

eye:-

artery/aorta:3.95

vein:4.45

lymphnode:4.93

peripheral blood:-

spleen:4.83

thymus:5.05

bone marrow:-

adipose:4.29

bone:-

skin:-

RNA-seq

cerebrum:0.34

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.77

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.13

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:142.10

prostate:56.30

ovary:111.80

testis:38.90

heart:76.60

muscle:20.10

esophagus:-

stomach:467.30

intestine:291.60

colon:152.60

liver/hepato:63.30

lung:112.40

bladder:-

kidney:145.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:62.20

breast:130.10

salivary:-

GeneChip

uterus:7.86

placenta:7.95

prostate:8.76

ovary:7.93

testis:7.69

heart:7.76

muscle:7.94

esophagus:8.88

stomach:7.99

intestine:8.11

colon:8.34

liver/hepato:7.90

lung:8.30

bladder:-

kidney:8.35

pituitary:7.58

thyroid/parathyroid:8.47

adrenal gland:7.81

pancreas:7.66

breast:8.13

salivary:8.47

CAGE

uterus:4.02

placenta:4.64

prostate:4.07

ovary:3.94

testis:3.91

heart:4.18

muscle:4.08

esophagus:4.62

stomach:-

intestine:4.73

colon:4.41

liver/hepato:4.74

lung:4.37

bladder:3.66

kidney:4.62

pituitary:3.55

thyroid/parathyroid:4.50

adrenal gland:-

pancreas:4.79

breast:4.29

salivary:4.94

RNA-seq

uterus:-

placenta:-

prostate:0.20

ovary:0.47

testis:0.00

heart:0.45

muscle:0.42

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.44

lung:1.01

bladder:-

kidney:0.52

pituitary:-

thyroid/parathyroid:0.79

adrenal gland:0.22

pancreas:-

breast:0.25

salivary:-

IDs

Refseq ID	NM_001008709
Gene ID	5499
Unigene ID	Hs.183994
Probe set ID	200846_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000172531
GTEx ID	ENSG00000172531

Orthologous Gene

Mouse[1]	NM_031868
Rat [0]

Chromosomal Region

11q13.2 [67,165,654 - 67,188,654]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004843	Metallophosphoesterase
IPR006186	Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

Gene Ontology (GO ID)

Biological Process

GO:0048754	branching morphogenesis of a tube
GO:0007049	cell cycle
GO:0051301	cell division
GO:0005977	glycogen metabolic process
GO:0030324	lung development
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0006470	protein amino acid dephosphorylation
GO:0005979	regulation of glycogen biosynthetic process
GO:0005981	regulation of glycogen catabolic process
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0019433	triglyceride catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043197	dendritic spine
GO:0042587	glycogen granule
GO:0070688	MLL5-L complex
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0043204	perikaryon
GO:0000164	protein phosphatase type 1 complex

Molecular Function

GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0004722	protein serine/threonine phosphatase activity
GO:0043021	ribonucleoprotein binding

protein phosphatase 1, catalytic subunit, alpha isoform

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function