tescalcin

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Synonym

Tescalcin, FLJ20607, TESC, tescalcin

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:50.60 peripheral blood:- spleen:- thymus:- bone marrow:39.40 adipose:- bone:- skin:19.20
GeneChip cerebrum:6.52 cerebellum:5.69 brain stem:5.88 corpus callosum/glia:5.75 pineal gland:- peripheral nerve:5.91 spine:5.45 retina:- eye:- artery/aorta:5.62 vein:6.07 lymphnode:6.42 peripheral blood:- spleen:6.03 thymus:5.68 bone marrow:8.71 adipose:5.67 bone:- skin:5.88
CAGE cerebrum:3.00 cerebellum:- brain stem:2.12 corpus callosum/glia:2.48 pineal gland:2.05 peripheral nerve:- spine:1.79 retina:- eye:- artery/aorta:2.12 vein:2.27 lymphnode:2.38 peripheral blood:- spleen:1.89 thymus:2.02 bone marrow:- adipose:2.01 bone:- skin:-
RNA-seq cerebrum:3.06 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.99 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.65 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:14.60 prostate:90.10 ovary:37.30 testis:38.90 heart:51.10 muscle:- esophagus:- stomach:106.20 intestine:- colon:25.40     liver/hepato:-        lung:9.80    bladder:- kidney:- pituitary:232 thyroid/parathyroid:- adrenal gland:50.80 pancreas:8.90 breast:- salivary:-
GeneChip uterus:5.47 placenta:5.93 prostate:6.43 ovary:5.71 testis:7.33 heart:7.28 muscle:5.52 esophagus:5.64 stomach:7.82 intestine:6.80 colon:5.78 liver/hepato:5.51 lung:6.13 bladder:- kidney:6.08 pituitary:6.50 thyroid/parathyroid:6.72 adrenal gland:7.51 pancreas:7.81 breast:6.07 salivary:10.48
CAGE uterus:1.84 placenta:2.08 prostate:2.74 ovary:1.61 testis:2.92 heart:3.89 muscle:1.88 esophagus:1.54 stomach:- intestine:1.41 colon:1.46     liver/hepato:1.01    lung:2.14 bladder:2.70 kidney:2.50 pituitary:2.20 thyroid/parathyroid:1.99 adrenal gland:- pancreas:5.14 breast:2.27 salivary:5.71
RNA-seq uterus:- placenta:- prostate:3.87 ovary:1.76 testis:4.31 heart:3.62 muscle:0.11 esophagus:- stomach:- intestine:- colon:2.19     liver/hepato:0.75        lung:3.10    bladder:- kidney:2.67 pituitary:- thyroid/parathyroid:1.72 adrenal gland:2.70 pancreas:- breast:2.13 salivary:-

Gene Information

IDs

Refseq ID NM_017899
Gene ID 54997
Unigene ID Hs.525709
Probe set ID 218872_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000088992
GTEx ID ENSG00000088992

Orthologous Gene

Mouse[2]  NM_021344
Rat[2]  NM_021344

Chromosomal Region

12q24.22  [117,476,728  -  117,537,284]

Gene Family (Interpro ID)

IPR002048  Calcium-binding EF-hand
IPR018249  EF-HAND 2

Link to Pubmed  (Pubmed ID)

8889548
11145610
11696366
12477932
12809501
14661968
15489334
16189514
17717601
18321853
19345287
20060826
21890473
21906983
22984264

Gene Ontology  (GO ID)

Biological Process

GO:0071300  cellular response to retinoic acid
GO:0008584  male gonad development
GO:0030219  megakaryocyte differentiation
GO:0008285  negative regulation of cell proliferation
GO:0010628  positive regulation of gene expression
GO:0030854  positive regulation of granulocyte differentiation
GO:0045654  positive regulation of megakaryocyte differentiation
GO:0032417  positive regulation of sodium:hydrogen antiporter activity
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051604  protein maturation
GO:0050821  protein stabilization
GO:0033628  regulation of cell adhesion mediated by integrin

Cellular Component

GO:0005737  cytoplasm
GO:0030027  lamellipodium
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0001726  ruffle
GO:0032587  ruffle membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0000287  magnesium ion binding
GO:0019212  phosphatase inhibitor activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004860  protein kinase inhibitor activity