phosphotyrosine interaction domain containing 1

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Synonym

HMFN2073, FLJ20701

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.19 cerebellum:4.49 brain stem:6.87 corpus callosum/glia:5.10 pineal gland:- peripheral nerve:6.69 spine:6.04 retina:- eye:- artery/aorta:7.37 vein:6.83 lymphnode:5.57 peripheral blood:- spleen:5.56 thymus:4.62 bone marrow:4.73 adipose:6.70 bone:- skin:6.35
CAGE cerebrum:3.32 cerebellum:- brain stem:3.05 corpus callosum/glia:2.70 pineal gland:2.33 peripheral nerve:- spine:2.91 retina:- eye:- artery/aorta:5.41 vein:3.86 lymphnode:3.25 peripheral blood:- spleen:3.08 thymus:1.03 bone marrow:- adipose:4.13 bone:- skin:-
RNA-seq cerebrum:0.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.45 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.59 placenta:6.55 prostate:6.32 ovary:6.39 testis:5.03 heart:5.95 muscle:4.92 esophagus:5.81 stomach:6.69 intestine:5.82 colon:6.63 liver/hepato:7.36 lung:6.18 bladder:- kidney:4.28 pituitary:5.20 thyroid/parathyroid:6.11 adrenal gland:7.20 pancreas:5.50 breast:5.99 salivary:4.81
CAGE uterus:4.03 placenta:3.94 prostate:4.03 ovary:3.94 testis:3.34 heart:4.19 muscle:3.54 esophagus:3.66 stomach:- intestine:3.46 colon:3.85     liver/hepato:4.92    lung:4.04 bladder:3.98 kidney:2.19 pituitary:3.20 thyroid/parathyroid:2.85 adrenal gland:- pancreas:2.34 breast:4.63 salivary:1.89
RNA-seq uterus:- placenta:- prostate:0.42 ovary:0.12 testis:0.12 heart:0.27 muscle:0.16 esophagus:- stomach:- intestine:- colon:0.73     liver/hepato:2.64        lung:0.53    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:1.36 adrenal gland:0.67 pancreas:- breast:0.23 salivary:-

Gene Information

IDs

Refseq ID NM_017933
Gene ID 55022
Unigene ID -
Probe set ID 219093_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000153823
GTEx ID ENSG00000153823

Orthologous Gene

Mouse[1]  NM_001003948
Rat[1]  NM_001110493

Chromosomal Region

2q36.3  [229,715,242  -  230,136,001]

Gene Family (Interpro ID)

IPR006020  Phosphotyrosine interaction domain
IPR011993  Pleckstrin homology-type

Link to Pubmed  (Pubmed ID)

8889548
12477932
14702039
15221005
15489334
16815647
17124247
18029348
19079291
19849947
20010835
20140872
20165904
20205790
21107309
22284633
22968630
23274913
23284291
23927930

Gene Ontology  (GO ID)

Biological Process

GO:0071345  cellular response to cytokine stimulus
GO:0071398  cellular response to fatty acid
GO:0071354  cellular response to interleukin-6
GO:0071356  cellular response to tumor necrosis factor
GO:0006112  energy reserve metabolic process
GO:0045444  fat cell differentiation
GO:0070584  mitochondrion morphogenesis
GO:0090005  negative regulation of establishment of protein localization in plasma membrane
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0070346  positive regulation of fat cell proliferation
GO:0010628  positive regulation of gene expression
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010635  regulation of mitochondrial fusion
GO:0051881  regulation of mitochondrial membrane potential

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus