WD repeat containing, antisense to TP53

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Synonym

WD repeat domain 79, WRAP53, WDR79, WD repeat protein 79, FLJ10385

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:46.20 cerebellum:88.20 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:41.10 artery/aorta:60 vein:66.60 lymphnode:30.30 peripheral blood:18.20 spleen:56.70 thymus:141.70 bone marrow:- adipose:- bone:38.40 skin:43.20
GeneChip cerebrum:6.78 cerebellum:6.93 brain stem:6.67 corpus callosum/glia:6.84 pineal gland:- peripheral nerve:6.75 spine:6.81 retina:- eye:- artery/aorta:6.89 vein:6.69 lymphnode:6.97 peripheral blood:- spleen:6.88 thymus:7.16 bone marrow:6.97 adipose:6.76 bone:- skin:7.01
CAGE cerebrum:1.86 cerebellum:- brain stem:1.85 corpus callosum/glia:2.16 pineal gland:1.49 peripheral nerve:- spine:1.36 retina:- eye:- artery/aorta:2.10 vein:1.86 lymphnode:1.97 peripheral blood:- spleen:2.05 thymus:2.66 bone marrow:- adipose:1.51 bone:- skin:-
RNA-seq cerebrum:0.21 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.18 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.11 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:54.60 prostate:11.30 ovary:- testis:99.50 heart:38.30 muscle:- esophagus:- stomach:63.70 intestine:97.20 colon:17     liver/hepato:-        lung:58.70    bladder:125.60 kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:9.30 salivary:-
GeneChip uterus:6.76 placenta:6.95 prostate:6.63 ovary:6.91 testis:7.20 heart:6.58 muscle:6.65 esophagus:6.83 stomach:6.74 intestine:6.79 colon:6.87 liver/hepato:6.69 lung:6.83 bladder:- kidney:6.82 pituitary:7.41 thyroid/parathyroid:6.97 adrenal gland:6.77 pancreas:6.80 breast:6.81 salivary:6.75
CAGE uterus:1.80 placenta:1.86 prostate:1.61 ovary:1.88 testis:2.29 heart:1.60 muscle:1.60 esophagus:1.70 stomach:- intestine:1.53 colon:1.78     liver/hepato:1.63    lung:2.12 bladder:1.45 kidney:2.03 pituitary:1.81 thyroid/parathyroid:1.80 adrenal gland:- pancreas:2.18 breast:1.36 salivary:1.89
RNA-seq uterus:- placenta:- prostate:0.86 ovary:0.66 testis:0.22 heart:0.24 muscle:0.64 esophagus:- stomach:- intestine:- colon:0.29     liver/hepato:0.69        lung:0.05    bladder:- kidney:0.34 pituitary:- thyroid/parathyroid:0.60 adrenal gland:0.72 pancreas:- breast:0.16 salivary:-

Gene Information

IDs

Refseq ID NM_018081
Gene ID 55135
Unigene ID Hs.437460
Probe set ID 44563_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000141499
GTEx ID ENSG00000141499

Orthologous Gene

Mouse[1]  NM_144824
Rat [0]  

Chromosomal Region

17p13.1  [7,589,389  -  7,606,820]

Gene Family (Interpro ID)

IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

8125298
12477932
14702039
15302935
15489334
17081983
17683073
18029348
18676680
18978339
19170196
19179534
19250907
19339270
19342896
19571673
19625176
19692168
19797907
20301779
20360068
20494116
21072240
21205863
21368886
21441950
21963094
22547674
22805008
22939629
23192612
23886136

Gene Ontology  (GO ID)

Biological Process

GO:0051973  positive regulation of telomerase activity
GO:0032203  telomere formation via telomerase

Cellular Component

GO:0015030  Cajal body
GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005697  telomerase holoenzyme complex

Molecular Function

GO:0005515  protein binding
GO:0003723  RNA binding