protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform

Synonym

PP2A, subunit A, R1-alpha isoform, PPP2R1A, PP2A, subunit A, PR65-alpha isoform, MGC786, Medium tumor antigen-associated 61 kDa protein

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1204.10

cerebellum:2065.40

brain stem:-

corpus callosum/glia:3149.40

pineal gland:148.30

peripheral nerve:153.40

spine:449.20

retina:-

eye:229.20

artery/aorta:1139.10

vein:1066.40

lymphnode:182

peripheral blood:819.80

spleen:1380.20

thymus:966.30

bone marrow:118.10

adipose:564.70

bone:1036.40

skin:465.60

GeneChip

cerebrum:8.41

cerebellum:8.55

brain stem:8.40

corpus callosum/glia:7.55

pineal gland:-

peripheral nerve:8.25

spine:7.82

retina:-

eye:-

artery/aorta:7.83

vein:8

lymphnode:7.56

peripheral blood:-

spleen:7.39

thymus:7.44

bone marrow:7.29

adipose:7.67

bone:-

skin:7.83

CAGE

cerebrum:5.06

cerebellum:-

brain stem:4.75

corpus callosum/glia:4.71

pineal gland:4.61

peripheral nerve:-

spine:4.27

retina:-

eye:-

artery/aorta:4.76

vein:4.65

lymphnode:4.71

peripheral blood:-

spleen:4.41

thymus:4.58

bone marrow:-

adipose:4.68

bone:-

skin:-

RNA-seq

cerebrum:5.79

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.46

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:5.67

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:1048

placenta:174.90

prostate:484.40

ovary:372.60

testis:212

heart:447

muscle:160.70

esophagus:685.60

stomach:446.10

intestine:810

colon:262.90

liver/hepato:42.20

lung:303

bladder:1130.50

kidney:613.40

pituitary:232

thyroid/parathyroid:2456.20

adrenal gland:3098

pancreas:80

breast:195.20

salivary:1313.60

GeneChip

uterus:7.91

placenta:7.38

prostate:8

ovary:8.18

testis:7.72

heart:8.12

muscle:7.86

esophagus:8.31

stomach:7.58

intestine:7.87

colon:8.05

liver/hepato:6.98

lung:7.57

bladder:-

kidney:8.03

pituitary:7.98

thyroid/parathyroid:7.74

adrenal gland:8.46

pancreas:7.57

breast:7.86

salivary:7.32

CAGE

uterus:4.66

placenta:4.50

prostate:4.78

ovary:5.02

testis:4.71

heart:4.92

muscle:5.09

esophagus:4.98

stomach:-

intestine:4.51

colon:4.70

liver/hepato:4.62

lung:4.27

bladder:4.71

kidney:4.80

pituitary:4.15

thyroid/parathyroid:4.69

adrenal gland:-

pancreas:4.45

breast:4.42

salivary:4.49

RNA-seq

uterus:-

placenta:-

prostate:6.30

ovary:6.15

testis:5.75

heart:5.96

muscle:6.37

esophagus:-

stomach:-

intestine:-

colon:5.30

liver/hepato:4.62

lung:5.54

bladder:-

kidney:5.86

pituitary:-

thyroid/parathyroid:5.88

adrenal gland:5.75

pancreas:-

breast:5.36

salivary:-

IDs

Refseq ID	NM_014225
Gene ID	5518
Unigene ID	Hs.467192
Probe set ID	200695_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000105568
GTEx ID	ENSG00000105568

Orthologous Gene

Mouse[5]	NM_016891
Rat [0]

Chromosomal Region

19q13.41 [52,693,274 - 52,730,687]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006672	ceramide metabolic process
GO:0007059	chromosome segregation
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0000086	G2/M transition of mitotic cell cycle
GO:0010467	gene expression
GO:0000188	inactivation of MAPK activity
GO:0006917	induction of apoptosis
GO:0000278	mitotic cell cycle
GO:0007084	mitotic nuclear envelope reassembly
GO:0016071	mRNA metabolic process
GO:0030308	negative regulation of cell growth
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0070262	peptidyl-serine dephosphorylation
GO:0006470	protein amino acid dephosphorylation
GO:0006461	protein complex assembly
GO:0030155	regulation of cell adhesion
GO:0045595	regulation of cell differentiation
GO:0006275	regulation of DNA replication
GO:0040008	regulation of growth
GO:0006355	regulation of transcription, DNA-dependent
GO:0030111	regulation of Wnt receptor signaling pathway
GO:0010033	response to organic substance
GO:0016070	RNA metabolic process
GO:0008380	RNA splicing
GO:0019932	second-messenger-mediated signaling

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0005829	cytosol
GO:0016020	membrane
GO:0015630	microtubule cytoskeleton
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0000159	protein phosphatase type 2A complex

Molecular Function

GO:0003823	antigen binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0008601	protein phosphatase type 2A regulator activity
GO:0004722	protein serine/threonine phosphatase activity

protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function