arginine vasopressin receptor 1A

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Synonym

AVPR1A, arginine vasopressin receptor 1A, AVPR V1a, Vasopressin V1a receptor, Antidiuretic hormone receptor 1a, AVPR1, V1aR

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:29.40 artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:40.30 bone:25.60 skin:24
GeneChip cerebrum:3.69 cerebellum:3.82 brain stem:3.72 corpus callosum/glia:3.58 pineal gland:- peripheral nerve:3.57 spine:3.58 retina:- eye:- artery/aorta:4.05 vein:4.28 lymphnode:3.70 peripheral blood:- spleen:3.50 thymus:3.61 bone marrow:3.92 adipose:4.19 bone:- skin:3.97
CAGE cerebrum:0.26 cerebellum:- brain stem:0.26 corpus callosum/glia:0.70 pineal gland:1.03 peripheral nerve:- spine:0.30 retina:- eye:- artery/aorta:1.91 vein:2.16 lymphnode:0.99 peripheral blood:- spleen:0.71 thymus:0.71 bone marrow:- adipose:3.89 bone:- skin:-
RNA-seq cerebrum:0.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.43 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.56 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:- prostate:- ovary:- testis:- heart:51.10 muscle:- esophagus:- stomach:42.50 intestine:- colon:-     liver/hepato:10.60        lung:14.70    bladder:- kidney:- pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:3.74 placenta:3.59 prostate:3.65 ovary:3.71 testis:3.60 heart:3.75 muscle:4.20 esophagus:3.61 stomach:3.73 intestine:3.83 colon:3.70 liver/hepato:4.19 lung:3.59 bladder:- kidney:3.75 pituitary:3.94 thyroid/parathyroid:3.81 adrenal gland:4.13 pancreas:4.19 breast:3.57 salivary:3.62
CAGE uterus:3.27 placenta:1.17 prostate:2.00 ovary:2.09 testis:0.96 heart:1.40 muscle:1.80 esophagus:1.68 stomach:- intestine:0.87 colon:1.08     liver/hepato:4.68    lung:0.80 bladder:2.46 kidney:2.15 pituitary:0.95 thyroid/parathyroid:1.78 adrenal gland:- pancreas:1.21 breast:2.47 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.86 ovary:0.60 testis:0.91 heart:0.60 muscle:0.23 esophagus:- stomach:- intestine:- colon:1.33     liver/hepato:2.73        lung:0.35    bladder:- kidney:1.19 pituitary:- thyroid/parathyroid:1.35 adrenal gland:1.31 pancreas:- breast:2.02 salivary:-

Gene Information

IDs

Refseq ID NM_000706
Gene ID 552
Unigene ID Hs.213137
Probe set ID 206252_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000166148
GTEx ID ENSG00000166148

Orthologous Gene

Mouse[2]  NM_016847
Rat [0]  

Chromosomal Region

12q14.2  [63,539,014  -  63,544,722]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR001817  Vasopressin receptor
IPR001224  Vasopressin V1A receptor

Link to Pubmed  (Pubmed ID)

8012384
8074728
8106369
8344200
8838314
9357056
9581826
10477084
10478574
10756113
10858434
12082568
12436935
12477932
12869559
14622255
14757828
15098001
15489334
15994199
16205790
16333859
16520824
16565083
16721832
16754659
17440932
17653244
17696996
17728669
17939166
18240029
18384079
18402937
18490926
18655900
18765804
19056558
19086053
19195791
19350216
19461995
19598235
19874574
19913121
20142561
20368512
20413116
20452058
20468064
20546835
20628086
20889332
21307861
21514569
21747049
21980412
22008661
22288734
22384070
22457427
22764113
24722188

Gene Ontology  (GO ID)

Biological Process

GO:0007202  activation of phospholipase C activity
GO:0008015  blood circulation
GO:0019722  calcium-mediated signaling
GO:0042631  cellular response to water deprivation
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0006091  generation of precursor metabolites and energy
GO:0007625  grooming behavior
GO:0002125  maternal aggressive behavior
GO:0042711  maternal behavior
GO:0014902  myotube differentiation
GO:0007621  negative regulation of female receptivity
GO:0051970  negative regulation of transmission of nerve impulse
GO:0043084  penile erection
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0032849  positive regulation of cellular pH reduction
GO:0014049  positive regulation of glutamate secretion
GO:0010460  positive regulation of heart rate
GO:0031394  positive regulation of prostaglandin biosynthetic process
GO:0003084  positive regulation of systemic arterial blood pressure
GO:0045907  positive regulation of vasoconstriction
GO:0001992  regulation of systemic arterial blood pressure by vasopressin
GO:0051412  response to corticosterone stimulus
GO:0035176  social behavior
GO:0042713  sperm ejaculation
GO:0021537  telencephalon development

Cellular Component

GO:0031410  cytoplasmic vesicle
GO:0005768  endosome
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0017046  peptide hormone binding
GO:0005515  protein binding
GO:0005080  protein kinase C binding
GO:0031894  V1A vasopressin receptor binding
GO:0005000  vasopressin receptor activity