ADP-ribosylation factor-like 8B

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Synonym

FLJ10702, ADP-ribosylation factor-like 10C, ADP-ribosylation factor-like protein 10C, ARL10C, ADP-ribosylation factor-like 8B, GIE1, ARL8B, ADP-ribosylation factor-like protein 8B, Gie1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:291.50 cerebellum:138.50 brain stem:- corpus callosum/glia:349.90 pineal gland:- peripheral nerve:153.40 spine:449.20 retina:- eye:64.60 artery/aorta:419.70 vein:- lymphnode:182 peripheral blood:218.60 spleen:113.40 thymus:386.50 bone marrow:59 adipose:80.70 bone:115.20 skin:134.40
GeneChip cerebrum:9.47 cerebellum:9.06 brain stem:9.58 corpus callosum/glia:9.11 pineal gland:- peripheral nerve:9.33 spine:9.35 retina:- eye:- artery/aorta:8.42 vein:8.58 lymphnode:8.45 peripheral blood:- spleen:8.22 thymus:8.48 bone marrow:8.24 adipose:8.50 bone:- skin:8.91
CAGE cerebrum:4.67 cerebellum:- brain stem:4.76 corpus callosum/glia:4.49 pineal gland:4.27 peripheral nerve:- spine:4.71 retina:- eye:- artery/aorta:4.17 vein:3.95 lymphnode:4.28 peripheral blood:- spleen:4.10 thymus:4.09 bone marrow:- adipose:4.47 bone:- skin:-
RNA-seq cerebrum:5.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.76 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.48 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:251.40 prostate:146.40 ovary:74.50 testis:294.20 heart:153.30 muscle:140.60 esophagus:- stomach:106.20 intestine:64.80 colon:59.40     liver/hepato:52.80        lung:112.40    bladder:376.80 kidney:52 pituitary:232 thyroid/parathyroid:163.70 adrenal gland:152.40 pancreas:88.90 breast:74.30 salivary:-
GeneChip uterus:8.76 placenta:9.25 prostate:8.89 ovary:8.72 testis:8.39 heart:8.49 muscle:8.69 esophagus:8.95 stomach:8.16 intestine:8.10 colon:7.63 liver/hepato:7.90 lung:8.79 bladder:- kidney:8.36 pituitary:8.49 thyroid/parathyroid:8.84 adrenal gland:8.59 pancreas:7.49 breast:8.79 salivary:7.86
CAGE uterus:4.12 placenta:4.93 prostate:4.19 ovary:4.18 testis:3.92 heart:4.26 muscle:4.71 esophagus:4.75 stomach:- intestine:4.04 colon:3.84     liver/hepato:4.13    lung:4.63 bladder:4.50 kidney:4.35 pituitary:4.26 thyroid/parathyroid:4.45 adrenal gland:- pancreas:3.85 breast:4.74 salivary:3.41
RNA-seq uterus:- placenta:- prostate:5.42 ovary:5.05 testis:4.93 heart:4.83 muscle:5.77 esophagus:- stomach:- intestine:- colon:5.00     liver/hepato:3.92        lung:5.01    bladder:- kidney:5.29 pituitary:- thyroid/parathyroid:5.64 adrenal gland:4.50 pancreas:- breast:4.87 salivary:-

Gene Information

IDs

Refseq ID NM_018184
Gene ID 55207
Unigene ID Hs.250009
Probe set ID 217852_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000134108
GTEx ID ENSG00000134108

Orthologous Gene

Mouse[3]  NM_026011
Rat[1]  NM_001024332

Chromosomal Region

3p26.1  [5,163,905  -  5,222,596]

Gene Family (Interpro ID)

IPR006689  ARF/SAR superfamily
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR006687  Small GTPase SAR1-type

Link to Pubmed  (Pubmed ID)

12477932
14702039
14871887
15331635
15489334
15761153
16169070
16537643
16650381
19056867
19322201
19398576
19946888
21139048
21674799
21802320
21824248
21832049
21890473
21906983
21963094
21987572
21988832
22053931
22505724
22993228
23000965
23166591
24088571

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0051301  cell division
GO:0007059  chromosome segregation
GO:0006184  GTP catabolic process
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0031902  late endosome membrane
GO:0005765  lysosomal membrane
GO:0030496  midbody
GO:0051233  spindle midzone

Molecular Function

GO:0043014  alpha-tubulin binding
GO:0048487  beta-tubulin binding
GO:0019003  GDP binding
GO:0005525  GTP binding
GO:0003924  GTPase activity