leprecan-like 1

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Synonym

MLAT4, Leprecan-like protein 1, LEPREL1, P3H2, leprecan-like 1, Prolyl 3-hydroxylase 2 precursor, Myxoid liposarcoma-associated protein 4, FLJ10718

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:58.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:113.40 thymus:12.90 bone marrow:- adipose:- bone:- skin:43.20
GeneChip cerebrum:5.41 cerebellum:5.26 brain stem:5.55 corpus callosum/glia:6.02 pineal gland:- peripheral nerve:5.97 spine:6.30 retina:- eye:- artery/aorta:6.77 vein:6.30 lymphnode:5.72 peripheral blood:- spleen:8.20 thymus:5.53 bone marrow:5.67 adipose:6.02 bone:- skin:6.63
CAGE cerebrum:1.30 cerebellum:- brain stem:2.20 corpus callosum/glia:2.48 pineal gland:1.72 peripheral nerve:- spine:2.32 retina:- eye:- artery/aorta:2.66 vein:2.18 lymphnode:1.82 peripheral blood:- spleen:4.06 thymus:1.36 bone marrow:- adipose:1.12 bone:- skin:-
RNA-seq cerebrum:0.86 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.98 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.12 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:118.50 placenta:10.90 prostate:236.60 ovary:186.30 testis:13 heart:12.80 muscle:- esophagus:- stomach:- intestine:97.20 colon:17     liver/hepato:-        lung:39.10    bladder:- kidney:197.50 pituitary:- thyroid/parathyroid:- adrenal gland:203.10 pancreas:- breast:27.90 salivary:-
GeneChip uterus:7.17 placenta:6.96 prostate:8.74 ovary:6.90 testis:5.33 heart:5.47 muscle:5.16 esophagus:6.09 stomach:6.07 intestine:6.13 colon:6.23 liver/hepato:5.69 lung:6.91 bladder:- kidney:7.93 pituitary:5.97 thyroid/parathyroid:5.44 adrenal gland:7.48 pancreas:5.50 breast:6.67 salivary:5.36
CAGE uterus:3.36 placenta:2.88 prostate:2.78 ovary:3.01 testis:1.85 heart:1.53 muscle:0.09 esophagus:2.76 stomach:- intestine:1.88 colon:2.54     liver/hepato:1.74    lung:3.74 bladder:1.81 kidney:4.80 pituitary:2.40 thyroid/parathyroid:1.27 adrenal gland:- pancreas:1.87 breast:1.68 salivary:1.28
RNA-seq uterus:- placenta:- prostate:2.85 ovary:3.55 testis:2.69 heart:1.25 muscle:0.24 esophagus:- stomach:- intestine:- colon:3.43     liver/hepato:1.44        lung:3.01    bladder:- kidney:5.98 pituitary:- thyroid/parathyroid:0.84 adrenal gland:1.85 pancreas:- breast:1.69 salivary:-

Gene Information

IDs

Refseq ID NM_001134418
Gene ID 55214
Unigene ID Hs.374191
Probe set ID 218717_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000090530
GTEx ID ENSG00000090530

Orthologous Gene

Mouse[1]  NM_173379
Rat[1]  NM_001025627

Chromosomal Region

3q28  [189,674,517  -  189,840,226]

Gene Family (Interpro ID)

IPR005123  Oxoglutarate/iron-dependent oxygenase
IPR006620  Prolyl 4-hydroxylase, alpha subunit

Link to Pubmed  (Pubmed ID)

8889548
10449603
12477932
14702039
15044469
15063763
15489334
16344560
18487197
18519826
19436308
20379614
21757687
21885030
21963094

Gene Ontology  (GO ID)

Biological Process

GO:0032963  collagen metabolic process
GO:0030198  extracellular matrix organization
GO:0008285  negative regulation of cell proliferation
GO:0019511  peptidyl-proline hydroxylation

Cellular Component

GO:0005604  basement membrane
GO:0005783  endoplasmic reticulum
GO:0005788  endoplasmic reticulum lumen
GO:0005794  Golgi apparatus

Molecular Function

GO:0005506  iron ion binding
GO:0031418  L-ascorbic acid binding
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019797  procollagen-proline 3-dioxygenase activity