protein phosphatase 2A activator, regulatory subunit 4

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Synonym

PTPA, PPP2R4, MGC2184, PP2A, Phosphotyrosyl phosphatase activator, PR53, PP2A, subunit B', PR53 isoform

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:282.10

cerebellum:314.80

brain stem:-

corpus callosum/glia:554.10

pineal gland:-

peripheral nerve:-

spine:224.60

retina:-

eye:141

artery/aorta:209.80

vein:266.60

lymphnode:80.90

peripheral blood:309.70

spleen:208

thymus:219

bone marrow:-

adipose:40.30

bone:243.10

skin:86.40

GeneChip

cerebrum:7.72

cerebellum:7.76

brain stem:7.60

corpus callosum/glia:7.39

pineal gland:-

peripheral nerve:7.34

spine:7.33

retina:-

eye:-

artery/aorta:7.27

vein:7.16

lymphnode:7.17

peripheral blood:-

spleen:7.30

thymus:7.14

bone marrow:6.99

adipose:7.04

bone:-

skin:7.23

CAGE

cerebrum:4.37

cerebellum:-

brain stem:4.20

corpus callosum/glia:4.23

pineal gland:3.80

peripheral nerve:-

spine:3.74

retina:-

eye:-

artery/aorta:3.99

vein:3.88

lymphnode:3.90

peripheral blood:-

spleen:4.01

thymus:3.90

bone marrow:-

adipose:3.53

bone:-

skin:-

RNA-seq

cerebrum:3.83

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.62

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.49

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:173.20

placenta:109.30

prostate:270.30

ovary:335.40

testis:281.20

heart:217.10

muscle:100.50

esophagus:685.60

stomach:127.50

intestine:194.40

colon:84.80

liver/hepato:42.20

lung:219.90

bladder:502.40

kidney:166.40

pituitary:-

thyroid/parathyroid:655

adrenal gland:406.30

pancreas:97.80

breast:111.50

salivary:-

GeneChip

uterus:7.30

placenta:6.56

prostate:7.50

ovary:7.30

testis:8.32

heart:7.65

muscle:7.66

esophagus:7.68

stomach:7.44

intestine:7.44

colon:7.39

liver/hepato:7.55

lung:7.33

bladder:-

kidney:7.72

pituitary:7.36

thyroid/parathyroid:7.56

adrenal gland:7.55

pancreas:6.72

breast:7.49

salivary:7.77

CAGE

uterus:3.97

placenta:3.90

prostate:4.03

ovary:4.02

testis:4.99

heart:4.07

muscle:4.08

esophagus:4.23

stomach:-

intestine:3.82

colon:3.90

liver/hepato:4.44

lung:3.82

bladder:3.77

kidney:4.20

pituitary:3.53

thyroid/parathyroid:4.13

adrenal gland:-

pancreas:3.87

breast:3.47

salivary:4.59

RNA-seq

uterus:-

placenta:-

prostate:1.25

ovary:2.29

testis:3.17

heart:1.27

muscle:0.55

esophagus:-

stomach:-

intestine:-

colon:1.63

liver/hepato:1.06

lung:0.20

bladder:-

kidney:1.07

pituitary:-

thyroid/parathyroid:2.76

adrenal gland:1.32

pancreas:-

breast:2.77

salivary:-

IDs

Refseq ID	NM_178000
Gene ID	5524
Unigene ID	Hs.400740
Probe set ID	208874_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000119383
GTEx ID	ENSG00000119383

Orthologous Gene

Mouse[2]	NM_138748
Rat [0]

Chromosomal Region

9q34.11 [131,873,229 - 131,911,225]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006200	ATP catabolic process
GO:0030472	mitotic spindle organization in nucleus
GO:0032515	negative regulation of phosphoprotein phosphatase activity
GO:0035308	negative regulation of protein amino acid dephosphorylation
GO:0043065	positive regulation of apoptosis
GO:0032516	positive regulation of phosphoprotein phosphatase activity
GO:0035307	positive regulation of protein amino acid dephosphorylation
GO:0006457	protein folding
GO:0000413	protein peptidyl-prolyl isomerization
GO:0043666	regulation of phosphoprotein phosphatase activity

Cellular Component

GO:0034704	calcium channel complex
GO:0005737	cytoplasm
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0000159	protein phosphatase type 2A complex

Molecular Function

GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0051721	protein phosphatase 2A binding
GO:0008601	protein phosphatase type 2A regulator activity
GO:0008160	protein tyrosine phosphatase activator activity
GO:0005102	receptor binding

protein phosphatase 2A activator, regulatory subunit 4

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function