dedicator of cytokinesis 10

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Synonym

Nbla10300, DKFZp781A1532, Dedicator of cytokinesis protein 10, DRIP2, DOCK10, Protein zizimin 3, KIAA0694, dedicator of cytokinesis 10, ZIZ3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.47 cerebellum:4.07 brain stem:7.10 corpus callosum/glia:8.04 pineal gland:- peripheral nerve:5.47 spine:7.24 retina:- eye:- artery/aorta:4.93 vein:4.26 lymphnode:6.55 peripheral blood:- spleen:7.24 thymus:6.97 bone marrow:4.95 adipose:4.80 bone:- skin:4.21
CAGE cerebrum:3.79 cerebellum:- brain stem:4.84 corpus callosum/glia:4.85 pineal gland:2.64 peripheral nerve:- spine:4.63 retina:- eye:- artery/aorta:3.40 vein:3.96 lymphnode:3.83 peripheral blood:- spleen:4.49 thymus:4.65 bone marrow:- adipose:3.16 bone:- skin:-
RNA-seq cerebrum:3.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.66 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:4.66 placenta:3.48 prostate:3.91 ovary:5.05 testis:3.55 heart:4 muscle:3.52 esophagus:4.11 stomach:4.51 intestine:4.23 colon:4.27 liver/hepato:4.18 lung:4.88 bladder:- kidney:3.81 pituitary:3.47 thyroid/parathyroid:3.82 adrenal gland:4.89 pancreas:2.91 breast:4.45 salivary:3.89
CAGE uterus:2.73 placenta:1.74 prostate:2.27 ovary:2.85 testis:1.80 heart:2.05 muscle:1.04 esophagus:2.52 stomach:- intestine:3.20 colon:2.76     liver/hepato:2.07    lung:3.23 bladder:2.68 kidney:2.23 pituitary:1.49 thyroid/parathyroid:1.61 adrenal gland:- pancreas:1.42 breast:2.11 salivary:1.28
RNA-seq uterus:- placenta:- prostate:0.70 ovary:2.26 testis:1.16 heart:0.39 muscle:0.34 esophagus:- stomach:- intestine:- colon:0.75     liver/hepato:0.87        lung:1.47    bladder:- kidney:1.17 pituitary:- thyroid/parathyroid:0.61 adrenal gland:2.48 pancreas:- breast:1.13 salivary:-

Gene Information

IDs

Refseq ID NM_014689
Gene ID 55619
Unigene ID -
Probe set ID 219279_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135905
GTEx ID ENSG00000135905

Orthologous Gene

Mouse[1]  NM_175291
Rat[1]  NM_175291

Chromosomal Region

2q36.2  [225,629,807  -  225,907,162]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

9734811
12168954
12432077
12477932
14702039
15489334
15710388
15815621
16189514
17081983
18499258
18835169
18854154
19946888
21139048
21514340
23967269
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007264  small GTPase mediated signal transduction

Molecular Function

GO:0005543  phospholipid binding
GO:0017048  Rho GTPase binding
GO:0005089  Rho guanyl-nucleotide exchange factor activity