protein kinase (cAMP-dependent, catalytic) inhibitor alpha

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Synonym

PRKACN1, PKIA, PKI-alpha, cAMP-dependent protein kinase inhibitor alpha

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:156.40 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:336.90 retina:118.60 eye:47 artery/aorta:- vein:66.60 lymphnode:30.30 peripheral blood:- spleen:37.80 thymus:25.80 bone marrow:- adipose:685.70 bone:- skin:19.20
GeneChip cerebrum:7.40 cerebellum:7.48 brain stem:7.10 corpus callosum/glia:6.53 pineal gland:- peripheral nerve:7.33 spine:7.20 retina:- eye:- artery/aorta:4.98 vein:5.37 lymphnode:5.51 peripheral blood:- spleen:4.96 thymus:7.10 bone marrow:4.53 adipose:4.87 bone:- skin:5.37
CAGE cerebrum:4.40 cerebellum:- brain stem:3.35 corpus callosum/glia:3.55 pineal gland:1.96 peripheral nerve:- spine:3.80 retina:- eye:- artery/aorta:1.28 vein:3.12 lymphnode:2.89 peripheral blood:- spleen:1.69 thymus:3.62 bone marrow:- adipose:2.52 bone:- skin:-
RNA-seq cerebrum:4.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:67.60 ovary:- testis:13 heart:306.50 muscle:823.70 esophagus:- stomach:- intestine:- colon:-     liver/hepato:73.90        lung:14.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:35.60 breast:- salivary:-
GeneChip uterus:4.44 placenta:4.44 prostate:6.50 ovary:4.77 testis:4.14 heart:7.45 muscle:10.08 esophagus:6.07 stomach:4.68 intestine:5.81 colon:4.88 liver/hepato:4.24 lung:5.52 bladder:- kidney:4.94 pituitary:6.36 thyroid/parathyroid:7.63 adrenal gland:4.72 pancreas:5.27 breast:4.77 salivary:4.87
CAGE uterus:1.65 placenta:1.25 prostate:2.70 ovary:2.06 testis:1.35 heart:4.32 muscle:5.97 esophagus:3.07 stomach:- intestine:1.74 colon:1.75     liver/hepato:0    lung:2.49 bladder:2.27 kidney:1.77 pituitary:3.26 thyroid/parathyroid:3.87 adrenal gland:- pancreas:0 breast:1.68 salivary:1.67
RNA-seq uterus:- placenta:- prostate:3.24 ovary:1.29 testis:0.76 heart:5.05 muscle:1.23 esophagus:- stomach:- intestine:- colon:0.87     liver/hepato:0.06        lung:2.28    bladder:- kidney:1.21 pituitary:- thyroid/parathyroid:3.98 adrenal gland:1.21 pancreas:- breast:0.37 salivary:-

Gene Information

IDs

Refseq ID NM_006823
Gene ID 5569
Unigene ID Hs.433700
Probe set ID 204612_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171033
GTEx ID ENSG00000171033

Orthologous Gene

Mouse[2]  NM_008862
Rat [0]  

Chromosomal Region

8q21.12  [79,428,374  -  79,517,502]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1710219
1770951
1862343
2434500
2989819
3456605
7836431
7905001
8027074
8805303
10026146
11978406
12477932
12798691
15489334
20195357
20451256
20485264
21833088
22219177
22504420
22833565

Gene Ontology  (GO ID)

Biological Process

GO:0042308  negative regulation of protein import into nucleus
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0010389  regulation of G2/M transition of mitotic cell cycle

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0004862  cAMP-dependent protein kinase inhibitor activity
GO:0034236  protein kinase A catalytic subunit binding