CNDP dipeptidase 2 (metallopeptidase M20 family)

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Synonym

CPGL, CNDP dipeptidase 2 (metallopeptidase M20 family), CN2, CNDP2, FLJ10830, Cytosolic nonspecific dipeptidase, CNDP dipeptidase 2, peptidase A, HsT2298, Glutamate carboxypeptidase-like protein 1, PEPA

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.87 cerebellum:7.56 brain stem:8.88 corpus callosum/glia:9.23 pineal gland:- peripheral nerve:8.46 spine:9.20 retina:- eye:- artery/aorta:7.77 vein:7.04 lymphnode:8.43 peripheral blood:- spleen:8.91 thymus:7.97 bone marrow:7.37 adipose:7.95 bone:- skin:7.90
CAGE cerebrum:4.44 cerebellum:- brain stem:4.74 corpus callosum/glia:5.10 pineal gland:3.85 peripheral nerve:- spine:4.79 retina:- eye:- artery/aorta:3.38 vein:3.93 lymphnode:4.27 peripheral blood:- spleen:4.85 thymus:3.53 bone marrow:- adipose:4.27 bone:- skin:-
RNA-seq cerebrum:0.34 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.46 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.32 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:8.07 placenta:8.23 prostate:9.65 ovary:8.55 testis:7.09 heart:7.75 muscle:7 esophagus:8.30 stomach:8.45 intestine:8.33 colon:8.37 liver/hepato:9.50 lung:8.56 bladder:- kidney:10.34 pituitary:8.12 thyroid/parathyroid:9.51 adrenal gland:7.65 pancreas:7.87 breast:8.43 salivary:7.99
CAGE uterus:3.86 placenta:4.56 prostate:4.13 ovary:3.76 testis:3.44 heart:3.77 muscle:3.21 esophagus:3.75 stomach:- intestine:5.49 colon:4.51     liver/hepato:5.16    lung:4.35 bladder:3.69 kidney:5.66 pituitary:3.63 thyroid/parathyroid:4.60 adrenal gland:- pancreas:4.37 breast:3.80 salivary:4.24
RNA-seq uterus:- placenta:- prostate:0.91 ovary:0.30 testis:0.10 heart:0.13 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.02     liver/hepato:0.79        lung:0.80    bladder:- kidney:1.71 pituitary:- thyroid/parathyroid:0.46 adrenal gland:0.78 pancreas:- breast:0.48 salivary:-

Gene Information

IDs

Refseq ID NM_001168499
Gene ID 55748
Unigene ID Hs.529027
Probe set ID 217752_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000133313
GTEx ID ENSG00000133313

Orthologous Gene

Mouse[2]  NM_023149
Rat[1]  NM_001010920

Chromosomal Region

18q22.3  [72,163,443  -  72,190,687]

Gene Family (Interpro ID)

IPR017153  Glutathione degradosome, DUG1
IPR002933  Peptidase M20

Link to Pubmed  (Pubmed ID)

8889548
12473676
12477932
14702039
15489334
17220478
18753673
18781797
19056867
19373489
20199107
21139048
21573905
21890473
21906983
22128300
22410244
22863883
22939629
23000965
23396134
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0034641  cellular nitrogen compound metabolic process
GO:0006750  glutathione biosynthetic process
GO:0006508  proteolysis
GO:0000096  sulfur amino acid metabolic process
GO:0006805  xenobiotic metabolic process

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0004180  carboxypeptidase activity
GO:0016805  dipeptidase activity
GO:0046872  metal ion binding
GO:0008237  metallopeptidase activity
GO:0034701  tripeptidase activity