intraflagellar transport 122 homolog (Chlamydomonas)

 jump to detail

Synonym

WD repeat domain 10, SPG, WDR10, IFT122, WD repeat protein 10, WDR10p, Intraflagellar transport 122 homolog, WDR140

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.50 cerebellum:6.38 brain stem:6.09 corpus callosum/glia:6.22 pineal gland:- peripheral nerve:6.47 spine:6.06 retina:- eye:- artery/aorta:6.60 vein:6.28 lymphnode:6.29 peripheral blood:- spleen:5.95 thymus:6.24 bone marrow:6.45 adipose:6.55 bone:- skin:6.64
CAGE cerebrum:3.46 cerebellum:- brain stem:2.88 corpus callosum/glia:3.32 pineal gland:3.35 peripheral nerve:- spine:2.92 retina:- eye:- artery/aorta:3.21 vein:2.85 lymphnode:2.54 peripheral blood:- spleen:2.39 thymus:3.07 bone marrow:- adipose:3.20 bone:- skin:-
RNA-seq cerebrum:2.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.85 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.49 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.67 placenta:5.61 prostate:6.39 ovary:7.14 testis:9.64 heart:6.12 muscle:5.72 esophagus:6.22 stomach:6.07 intestine:5.91 colon:6.24 liver/hepato:6.02 lung:6.72 bladder:- kidney:6.71 pituitary:7.10 thyroid/parathyroid:7.12 adrenal gland:6.21 pancreas:6.24 breast:6.99 salivary:5.78
CAGE uterus:3.52 placenta:2.33 prostate:2.93 ovary:3.38 testis:5.34 heart:3.15 muscle:2.48 esophagus:2.47 stomach:- intestine:2.38 colon:2.78     liver/hepato:2.55    lung:2.83 bladder:2.89 kidney:3.27 pituitary:4.03 thyroid/parathyroid:3.10 adrenal gland:- pancreas:2.81 breast:2.64 salivary:2.95
RNA-seq uterus:- placenta:- prostate:2.45 ovary:2.86 testis:2.17 heart:1.32 muscle:0.96 esophagus:- stomach:- intestine:- colon:1.55     liver/hepato:0.90        lung:2.16    bladder:- kidney:2.31 pituitary:- thyroid/parathyroid:2.58 adrenal gland:1.85 pancreas:- breast:1.48 salivary:-

Gene Information

IDs

Refseq ID NM_018262
Gene ID 55764
Unigene ID -
Probe set ID 220744_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000163913
GTEx ID ENSG00000163913

Orthologous Gene

Mouse[2]  NM_001167763, NM_031177
Rat[2]  NM_001167763, NM_031177

Chromosomal Region

3q21.3  [129,158,968  -  129,239,198]

Gene Family (Interpro ID)

IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

8125298
11242542
12477932
14702039
16344560
16751776
18029348
19946888
20301743
20493458
21890473
21906983
22190034
22505724
24027799
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0048593  camera-type eye morphogenesis
GO:0060830  ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271  cilium morphogenesis
GO:0010172  embryonic body morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0035050  embryonic heart tube development
GO:0060173  limb development
GO:0045879  negative regulation of smoothened signaling pathway
GO:0001843  neural tube closure
GO:0060831  smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Cellular Component

GO:0005737  cytoplasm
GO:0030991  intraflagellar transport particle A
GO:0005932  microtubule basal body
GO:0032391  photoreceptor connecting cilium

Molecular Function

GO:0005515  protein binding