chondroitin sulfate N-acetylgalactosaminyltransferase 1

 jump to detail

Synonym

beta4GalNAcT, ChGn, FLJ11264

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.43 cerebellum:4.32 brain stem:6.12 corpus callosum/glia:6.36 pineal gland:- peripheral nerve:7.20 spine:6.49 retina:- eye:- artery/aorta:6.20 vein:7.71 lymphnode:5.85 peripheral blood:- spleen:5.42 thymus:5.26 bone marrow:7.44 adipose:6.42 bone:- skin:5.58
CAGE cerebrum:3.50 cerebellum:- brain stem:2.74 corpus callosum/glia:3.22 pineal gland:1.97 peripheral nerve:- spine:3.39 retina:- eye:- artery/aorta:3.18 vein:3.10 lymphnode:2.83 peripheral blood:- spleen:2.77 thymus:2.23 bone marrow:- adipose:3.21 bone:- skin:-
RNA-seq cerebrum:3.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.95 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.43 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.95 placenta:8.43 prostate:8.49 ovary:7.08 testis:4.40 heart:7.36 muscle:4.82 esophagus:5.68 stomach:5.87 intestine:5.38 colon:4.97 liver/hepato:3.93 lung:6.12 bladder:- kidney:5.03 pituitary:5.24 thyroid/parathyroid:9.07 adrenal gland:6.52 pancreas:5.51 breast:5.55 salivary:5.35
CAGE uterus:3.02 placenta:3.63 prostate:3.12 ovary:3.47 testis:1.88 heart:3.10 muscle:1.45 esophagus:2.62 stomach:- intestine:1.84 colon:2.11     liver/hepato:0.55    lung:2.70 bladder:2.99 kidney:1.86 pituitary:2.55 thyroid/parathyroid:3.81 adrenal gland:- pancreas:3.02 breast:2.83 salivary:1.75
RNA-seq uterus:- placenta:- prostate:3.97 ovary:3.30 testis:2.82 heart:3.65 muscle:1.01 esophagus:- stomach:- intestine:- colon:2.96     liver/hepato:0.89        lung:3.21    bladder:- kidney:2.36 pituitary:- thyroid/parathyroid:3.93 adrenal gland:3.72 pancreas:- breast:2.43 salivary:-

Gene Information

IDs

Refseq ID NM_018371
Gene ID 55790
Unigene ID Hs.613729
Probe set ID 219049_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000147408
GTEx ID ENSG00000147408

Orthologous Gene

Mouse[4]  NM_172753
Rat[1]  NM_001107309

Chromosomal Region

8p21.3  [19,261,672  -  19,615,540]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11514575
11788602
12163485
12446672
12477932
12975309
14702039
15489334
16344560
17145758
19701759
19730683
20379614
21160489
22156920
22939629
23726668
23748413

Gene Ontology  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0005975  carbohydrate metabolic process
GO:0051216  cartilage development
GO:0008283  cell proliferation
GO:0008037  cell recognition
GO:0030206  chondroitin sulfate biosynthetic process
GO:0030204  chondroitin sulfate metabolic process
GO:0050650  chondroitin sulfate proteoglycan biosynthetic process
GO:0050653  chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0050651  dermatan sulfate proteoglycan biosynthetic process
GO:0001958  endochondral ossification
GO:0030198  extracellular matrix organization
GO:0030203  glycosaminoglycan metabolic process
GO:0015014  heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0030210  heparin biosynthetic process
GO:0007399  nervous system development
GO:0030166  proteoglycan biosynthetic process
GO:0046398  UDP-glucuronate metabolic process
GO:0019276  UDP-N-acetylgalactosamine metabolic process

Cellular Component

GO:0032580  Golgi cisterna membrane
GO:0000139  Golgi membrane
GO:0030173  integral to Golgi membrane
GO:0005622  intracellular

Molecular Function

GO:0008376  acetylgalactosaminyltransferase activity
GO:0047238  glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
GO:0015020  glucuronosyltransferase activity
GO:0047237  glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
GO:0046872  metal ion binding
GO:0008955  peptidoglycan glycosyltransferase activity