transcriptional regulating factor 1

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Synonym

breast cancer anti-estrogen resistance 2, Transcriptional-regulating protein 132, Zinc finger protein rapa, dJ139D8.5, RP1-139D8.5, TRERF1, HSA277276, TREP132, Transcriptional-regulating factor 1, RAPA, Zinc finger transcription factor TReP-132, TReP-132, BCAR2, transcriptional regulating factor 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:30.30 peripheral blood:- spleen:- thymus:38.70 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:1.86 cerebellum:- brain stem:1.30 corpus callosum/glia:1.51 pineal gland:1.08 peripheral nerve:- spine:1.37 retina:- eye:- artery/aorta:2.17 vein:2.22 lymphnode:2.41 peripheral blood:- spleen:1.80 thymus:3.01 bone marrow:- adipose:1.25 bone:- skin:-
RNA-seq cerebrum:1.02 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.62 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:8.70 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:2.60 placenta:1.11 prostate:2.42 ovary:1.95 testis:2.43 heart:1.08 muscle:0.49 esophagus:2.07 stomach:- intestine:1.77 colon:1.94     liver/hepato:0.36    lung:1.73 bladder:2.03 kidney:1.30 pituitary:2.05 thyroid/parathyroid:0.93 adrenal gland:- pancreas:0.94 breast:0.90 salivary:1.00
RNA-seq uterus:- placenta:- prostate:1.92 ovary:2.13 testis:1.95 heart:0.40 muscle:0.11 esophagus:- stomach:- intestine:- colon:1.03     liver/hepato:0.17        lung:0.96    bladder:- kidney:1.52 pituitary:- thyroid/parathyroid:0.65 adrenal gland:1.48 pancreas:- breast:0.84 salivary:-

Gene Information

IDs

Refseq ID NM_033502
Gene ID 55809
Unigene ID Hs.485392
Probe set ID -
Ensembl ID ENSG00000124496
GTEx ID ENSG00000124496

Orthologous Gene

Mouse[2]  NM_001097623, NM_172622
Rat[1]  NM_001108199, NM_172622

Chromosomal Region

6p21.1  [42,192,669  -  42,419,789]

Gene Family (Interpro ID)

IPR009057  Homeodomain-like
IPR012287  Homeodomain-related
IPR001005  SANT, DNA-binding
IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

9259413
11349124
12101186
12530663
14574404
14702039
15072559
15302935
15899840
17015480
19322201
19471022
19913121
20379614
20628086
21258344
21890473
21906983
21987572
23667531
23752268

Gene Ontology  (GO ID)

Biological Process

GO:0006707  cholesterol catabolic process
GO:0042592  homeostatic process
GO:0007275  multicellular organismal development
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0046885  regulation of hormone biosynthetic process
GO:0006694  steroid biosynthetic process

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0046872  metal ion binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding