phosphoprotein associated with glycosphingolipid microdomains 1

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Synonym

Transmembrane phosphoprotein Cbp, Transmembrane adapter protein PAG, FLJ37858, Csk-binding protein, PAG1, PAG, MGC138364

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:55.70 cerebellum:50.40 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:336.90 retina:118.60 eye:76.40 artery/aorta:- vein:- lymphnode:202.20 peripheral blood:72.90 spleen:94.50 thymus:90.20 bone marrow:275.50 adipose:- bone:12.80 skin:33.60
GeneChip nodata
CAGE cerebrum:2.76 cerebellum:- brain stem:2.72 corpus callosum/glia:2.66 pineal gland:2.89 peripheral nerve:- spine:3.24 retina:- eye:- artery/aorta:2.89 vein:3.32 lymphnode:3.49 peripheral blood:- spleen:3.27 thymus:3.38 bone marrow:- adipose:2.12 bone:- skin:-
RNA-seq cerebrum:2.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.92 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.62 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:43.70 prostate:33.80 ovary:- testis:4.30 heart:12.80 muscle:- esophagus:- stomach:127.50 intestine:- colon:42.40     liver/hepato:31.70        lung:97.80    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip nodata
CAGE uterus:1.59 placenta:2.68 prostate:1.86 ovary:1.85 testis:1.57 heart:2.77 muscle:1.90 esophagus:1.78 stomach:- intestine:3.54 colon:3.45     liver/hepato:2.24    lung:3.57 bladder:2.33 kidney:1.53 pituitary:2.20 thyroid/parathyroid:0.95 adrenal gland:- pancreas:3.59 breast:2.59 salivary:1.89
RNA-seq uterus:- placenta:- prostate:1.41 ovary:1.38 testis:1.02 heart:1.63 muscle:0.39 esophagus:- stomach:- intestine:- colon:1.36     liver/hepato:1.21        lung:2.87    bladder:- kidney:1.43 pituitary:- thyroid/parathyroid:0.95 adrenal gland:2.18 pancreas:- breast:1.07 salivary:-

Gene Information

IDs

Refseq ID NM_018440
Gene ID 55824
Unigene ID Hs.266175
Probe set ID -
Ensembl ID ENSG00000076641
GTEx ID ENSG00000076641

Orthologous Gene

Mouse[2]  NM_001195031, NM_053182
Rat[2]  NM_001195031, NM_053182

Chromosomal Region

8q21.13  [81,882,526  -  82,024,303]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9334312
10790433
11163757
11684085
12477932
12665526
14665621
14702039
15489334
16160011
16413409
16636672
16947079
17143285
17389760
18056706
18070987
19581936
19913121
20379614
20388373
20561033
20628086
21092590
21156787
21388951
21822266
22027792
22659621
22994656
23022100
23671581
24163127

Gene Ontology  (GO ID)

Biological Process

GO:0007173  epidermal growth factor receptor signaling pathway
GO:0050868  negative regulation of T cell activation
GO:0050863  regulation of T cell activation
GO:0007165  signal transduction
GO:0050852  T cell receptor signaling pathway

Cellular Component

GO:0016021  integral to membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding
GO:0042169  SH2 domain binding
GO:0005070  SH3/SH2 adaptor activity