protein kinase C, iota

Synonym

Atypical protein kinase C-lambda/iota, PKCI, DXS1179E, nPKC-iota, Protein kinase C iota type, PRKCI, MGC26534, aPKC-lambda/iota, PRKC-lambda/iota, protein kinase C, iota

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:28.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:52.90

artery/aorta:-

vein:-

lymphnode:60.70

peripheral blood:-

spleen:37.80

thymus:-

bone marrow:19.70

adipose:40.30

bone:25.60

skin:9.60

GeneChip

cerebrum:7.59

cerebellum:7.60

brain stem:7.30

corpus callosum/glia:7.15

pineal gland:-

peripheral nerve:7.92

spine:7.28

retina:-

eye:-

artery/aorta:7.05

vein:7.37

lymphnode:7.21

peripheral blood:-

spleen:7.24

thymus:7.76

bone marrow:6.30

adipose:7.13

bone:-

skin:7.21

CAGE

cerebrum:3.14

cerebellum:-

brain stem:2.90

corpus callosum/glia:2.81

pineal gland:2.84

peripheral nerve:-

spine:2.79

retina:-

eye:-

artery/aorta:3.04

vein:2.49

lymphnode:2.62

peripheral blood:-

spleen:2.65

thymus:3.11

bone marrow:-

adipose:2.88

bone:-

skin:-

RNA-seq

cerebrum:3.16

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.57

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.39

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:7.30

prostate:33.80

ovary:-

testis:56.20

heart:38.30

muscle:40.20

esophagus:-

stomach:42.50

intestine:-

colon:8.50

liver/hepato:52.80

lung:29.30

bladder:-

kidney:41.60

pituitary:463.90

thyroid/parathyroid:-

adrenal gland:-

pancreas:17.80

breast:37.20

salivary:-

GeneChip

uterus:7.97

placenta:7.15

prostate:8.85

ovary:8.77

testis:8.06

heart:7.55

muscle:7

esophagus:8.23

stomach:8.71

intestine:7.65

colon:7.44

liver/hepato:6.85

lung:7.88

bladder:-

kidney:8.07

pituitary:7.60

thyroid/parathyroid:8.88

adrenal gland:7.20

pancreas:7.17

breast:8.03

salivary:8.83

CAGE

uterus:3.36

placenta:2.81

prostate:3.49

ovary:3.48

testis:3.42

heart:2.66

muscle:2.19

esophagus:3.28

stomach:-

intestine:3.19

colon:3.08

liver/hepato:2.30

lung:3.42

bladder:3.26

kidney:3.30

pituitary:3.44

thyroid/parathyroid:3.79

adrenal gland:-

pancreas:2.66

breast:2.74

salivary:3.77

RNA-seq

uterus:-

placenta:-

prostate:3.69

ovary:3.64

testis:3.44

heart:2.19

muscle:2.26

esophagus:-

stomach:-

intestine:-

colon:2.71

liver/hepato:1.52

lung:3.26

bladder:-

kidney:3.45

pituitary:-

thyroid/parathyroid:3.47

adrenal gland:2.25

pancreas:-

breast:2.53

salivary:-

IDs

Refseq ID	NM_002740
Gene ID	5584
Unigene ID	Hs.478199
Probe set ID	209678_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000163558
GTEx ID	ENSG00000163558

Orthologous Gene

Mouse[2]	NM_008857
Rat[1]	NM_032059

Chromosomal Region

3q26.2 [169,940,153 - 170,023,769]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0007015	actin filament organization
GO:0034329	cell junction assembly
GO:0016477	cell migration
GO:0045216	cell-cell junction organization
GO:0032869	cellular response to insulin stimulus
GO:0007010	cytoskeleton organization
GO:0035089	establishment of apical/basal cell polarity
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
GO:0042462	eye photoreceptor cell development
GO:0048194	Golgi vesicle budding
GO:0016044	membrane organization
GO:0043066	negative regulation of apoptosis
GO:0034351	negative regulation of glial cell apoptosis
GO:0043524	negative regulation of neuron apoptosis
GO:0048011	nerve growth factor receptor signaling pathway
GO:0090004	positive regulation of establishment of protein localization in plasma membrane
GO:0060252	positive regulation of glial cell proliferation
GO:0046326	positive regulation of glucose import
GO:0010976	positive regulation of neuron projection development
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0006468	protein amino acid phosphorylation
GO:0006612	protein targeting to membrane
GO:0070555	response to interleukin-1
GO:0046903	secretion
GO:0070830	tight junction assembly
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0016324	apical plasma membrane
GO:0031252	cell leading edge
GO:0005829	cytosol
GO:0005768	endosome
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0000133	polarisome
GO:0043220	Schmidt-Lanterman cleft

Molecular Function

GO:0005524	ATP binding
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0004672	protein kinase activity
GO:0004697	protein kinase C activity
GO:0004674	protein serine/threonine kinase activity
GO:0008270	zinc ion binding

protein kinase C, iota

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function