protein kinase D1

Synonym

PKCM, nPKC-mu, Protein kinase C mu type, PRKD1, PKC-MU, protein kinase D1, PKC-mu, nPKC-D1, PKD, Serine/threonine-protein kinase D1, PKD1, Protein kinase D, PRKCM

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:16.60

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:296.70

peripheral nerve:30.70

spine:224.60

retina:237.30

eye:29.40

artery/aorta:-

vein:-

lymphnode:10.10

peripheral blood:-

spleen:-

thymus:-

bone marrow:19.70

adipose:-

bone:64

skin:28.80

GeneChip

cerebrum:5.08

cerebellum:4.33

brain stem:4.89

corpus callosum/glia:5.43

pineal gland:-

peripheral nerve:6.29

spine:6.27

retina:-

eye:-

artery/aorta:5.89

vein:6.12

lymphnode:4.53

peripheral blood:-

spleen:4.42

thymus:4.44

bone marrow:4.09

adipose:5.14

bone:-

skin:4.60

CAGE

cerebrum:2.50

cerebellum:-

brain stem:2.47

corpus callosum/glia:2.41

pineal gland:3.81

peripheral nerve:-

spine:3.52

retina:-

eye:-

artery/aorta:3.38

vein:2.18

lymphnode:1.41

peripheral blood:-

spleen:1.54

thymus:0.94

bone marrow:-

adipose:2.35

bone:-

skin:-

RNA-seq

cerebrum:1.58

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.12

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.85

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:54.70

placenta:25.50

prostate:45.10

ovary:-

testis:47.60

heart:25.50

muscle:20.10

esophagus:-

stomach:21.20

intestine:-

colon:-

liver/hepato:-

lung:44

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:27.90

salivary:-

GeneChip

uterus:6.05

placenta:4.49

prostate:7.69

ovary:6.23

testis:6.47

heart:5.08

muscle:4.41

esophagus:4.49

stomach:4.96

intestine:4.95

colon:4.59

liver/hepato:4.31

lung:5.46

bladder:-

kidney:6.39

pituitary:5.60

thyroid/parathyroid:5.88

adrenal gland:6.09

pancreas:4.50

breast:5.61

salivary:4.63

CAGE

uterus:2.56

placenta:1.20

prostate:3.06

ovary:2.68

testis:3.31

heart:2.32

muscle:1.66

esophagus:1.72

stomach:-

intestine:1.33

colon:2.48

liver/hepato:0.78

lung:2.96

bladder:2.70

kidney:2.96

pituitary:2.95

thyroid/parathyroid:2.16

adrenal gland:-

pancreas:2.71

breast:3.54

salivary:1.28

RNA-seq

uterus:-

placenta:-

prostate:3.49

ovary:3.31

testis:3.82

heart:1.14

muscle:0.54

esophagus:-

stomach:-

intestine:-

colon:1.99

liver/hepato:0.67

lung:1.85

bladder:-

kidney:3.43

pituitary:-

thyroid/parathyroid:2.11

adrenal gland:1.79

pancreas:-

breast:2.04

salivary:-

IDs

Refseq ID	NM_002742
Gene ID	5587
Unigene ID	Hs.508999
Probe set ID	205880_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000184304
GTEx ID	ENSG00000184304

Orthologous Gene

Mouse[1]	NM_008858
Rat[1]	NM_008858

Chromosomal Region

14q12 [30,045,687 - 30,661,104]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001849	Pleckstrin homology
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0006915	apoptosis
GO:0008283	cell proliferation
GO:0034599	cellular response to oxidative stress
GO:0007030	Golgi organization
GO:0048193	Golgi vesicle transport
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0007229	integrin-mediated signaling pathway
GO:0060548	negative regulation of cell death
GO:0045806	negative regulation of endocytosis
GO:0018105	peptidyl-serine phosphorylation
GO:0045766	positive regulation of angiogenesis
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0032793	positive regulation of CREB transcription factor activity
GO:0010595	positive regulation of endothelial cell migration
GO:0001938	positive regulation of endothelial cell proliferation
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0010976	positive regulation of neuron projection development
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0045669	positive regulation of osteoblast differentiation
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046777	protein amino acid autophosphorylation
GO:0007243	protein kinase cascade
GO:0010837	regulation of keratinocyte proliferation
GO:0007165	signal transduction
GO:0030148	sphingolipid biosynthetic process
GO:0006665	sphingolipid metabolic process
GO:0048010	vascular endothelial growth factor receptor signaling pathway

Cellular Component

GO:0005938	cell cortex
GO:0005911	cell-cell junction
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005794	Golgi apparatus
GO:0005887	integral to plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0005802	trans-Golgi network

Molecular Function

GO:0005524	ATP binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0004697	protein kinase C activity
GO:0004674	protein serine/threonine kinase activity

protein kinase D1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function