sulfatase 2

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Synonym

Extracellular sulfatase Sulf-2 precursor, HSulf-2, sulfatase 2, KIAA1247, UNQ559/PRO1120, SULF-2, HSULF-2, SULF2, FLJ90554, MGC126411, DKFZp313E091

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:184 spine:- retina:- eye:117.50 artery/aorta:89.90 vein:- lymphnode:70.80 peripheral blood:36.40 spleen:18.90 thymus:38.70 bone marrow:59 adipose:40.30 bone:102.40 skin:110.40
GeneChip nodata
CAGE cerebrum:3.16 cerebellum:- brain stem:3.75 corpus callosum/glia:3.27 pineal gland:2.94 peripheral nerve:- spine:2.88 retina:- eye:- artery/aorta:3.73 vein:3.69 lymphnode:3.84 peripheral blood:- spleen:2.14 thymus:1.85 bone marrow:- adipose:3.61 bone:- skin:-
RNA-seq cerebrum:0.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.57 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:127.60 placenta:72.90 prostate:11.30 ovary:74.50 testis:47.60 heart:140.50 muscle:60.30 esophagus:- stomach:127.50 intestine:- colon:127.20     liver/hepato:63.30        lung:53.80    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:316 salivary:-
GeneChip nodata
CAGE uterus:4.79 placenta:3.38 prostate:3.33 ovary:5.00 testis:3.77 heart:3.68 muscle:3.30 esophagus:3.88 stomach:- intestine:2.87 colon:3.52     liver/hepato:3.29    lung:2.67 bladder:3.58 kidney:3.90 pituitary:3.71 thyroid/parathyroid:3.49 adrenal gland:- pancreas:1.59 breast:3.06 salivary:1.75
RNA-seq uterus:- placenta:- prostate:0.00 ovary:1.18 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.26    bladder:- kidney:1.08 pituitary:- thyroid/parathyroid:0.00 adrenal gland:2.22 pancreas:- breast:0.18 salivary:-

Gene Information

IDs

Refseq ID NM_198596
Gene ID 55959
Unigene ID Hs.162016
Probe set ID -
Ensembl ID ENSG00000196562
GTEx ID ENSG00000196562

Orthologous Gene

Mouse[1]  NM_028072
Rat[1]  NM_001034927

Chromosomal Region

20q13.13  [46,285,092  -  46,415,360]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10574462
11549316
11780052
12107413
12168954
12368295
12477932
12975309
14702039
15489334
16192265
16331886
16417632
18507859
18687675
18937294
19190338
19520866
19855436
20707913
20725905
21040406
21347431
21441931
21599997
21890473
21968018
22158045
22293178
22410125
22623531
23418199
23457216
23480519
23950901
24124496
24726914

Gene Ontology  (GO ID)

Biological Process

GO:0060348  bone development
GO:0051216  cartilage development
GO:0002063  chondrocyte development
GO:0048706  embryonic skeletal system development
GO:0014846  esophagus smooth muscle contraction
GO:0032836  glomerular basement membrane development
GO:0003094  glomerular filtration
GO:0030201  heparan sulfate proteoglycan metabolic process
GO:0060384  innervation
GO:0001822  kidney development
GO:0040037  negative regulation of fibroblast growth factor receptor signaling pathway
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0010575  positive regulation vascular endothelial growth factor production

Cellular Component

GO:0009986  cell surface
GO:0005783  endoplasmic reticulum
GO:0005615  extracellular space
GO:0005795  Golgi stack
GO:0005886  plasma membrane

Molecular Function

GO:0004065  arylsulfatase activity
GO:0005509  calcium ion binding
GO:0008449  N-acetylglucosamine-6-sulfatase activity