protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)

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Synonym

PRKRIR, P52RIPK, THAP0, p58IPK-interacting protein, MGC102750, THAP domain-containing protein 0, Death-associated protein 4, DAP4, P52rIPK

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.60 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:237.30 eye:5.90 artery/aorta:119.90 vein:66.60 lymphnode:141.50 peripheral blood:- spleen:18.90 thymus:- bone marrow:19.70 adipose:- bone:25.60 skin:43.20
GeneChip cerebrum:6.41 cerebellum:6.28 brain stem:6.35 corpus callosum/glia:6.49 pineal gland:- peripheral nerve:6.77 spine:6.50 retina:- eye:- artery/aorta:6.73 vein:6.59 lymphnode:7.23 peripheral blood:- spleen:7.35 thymus:7.54 bone marrow:6.64 adipose:7.20 bone:- skin:6.91
CAGE cerebrum:1.97 cerebellum:- brain stem:1.97 corpus callosum/glia:1.53 pineal gland:1.88 peripheral nerve:- spine:1.82 retina:- eye:- artery/aorta:1.68 vein:1.76 lymphnode:1.87 peripheral blood:- spleen:2.52 thymus:3.04 bone marrow:- adipose:2.10 bone:- skin:-
RNA-seq cerebrum:3.24 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.63 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.56 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:61.90 prostate:78.90 ovary:37.30 testis:8.70 heart:89.40 muscle:20.10 esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:52.80        lung:39.10    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:53.30 breast:120.80 salivary:-
GeneChip uterus:7.26 placenta:7.38 prostate:7.04 ovary:7.40 testis:6.89 heart:6.60 muscle:7.65 esophagus:5.98 stomach:6.93 intestine:7.32 colon:6.41 liver/hepato:6.46 lung:6.92 bladder:- kidney:6.36 pituitary:5.82 thyroid/parathyroid:6.91 adrenal gland:6.99 pancreas:7.13 breast:7.10 salivary:6.22
CAGE uterus:1.90 placenta:2.40 prostate:1.85 ovary:2.13 testis:2.27 heart:2.13 muscle:1.55 esophagus:1.98 stomach:- intestine:2.11 colon:2.15     liver/hepato:2.45    lung:2.08 bladder:1.95 kidney:2.23 pituitary:1.96 thyroid/parathyroid:2.15 adrenal gland:- pancreas:1.42 breast:2.74 salivary:2.12
RNA-seq uterus:- placenta:- prostate:3.65 ovary:4.47 testis:3.95 heart:2.86 muscle:2.76 esophagus:- stomach:- intestine:- colon:3.47     liver/hepato:2.63        lung:3.34    bladder:- kidney:3.59 pituitary:- thyroid/parathyroid:4.08 adrenal gland:4.04 pancreas:- breast:4.01 salivary:-

Gene Information

IDs

Refseq ID NM_004705
Gene ID 5612
Unigene ID Hs.503315
Probe set ID 209323_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000137492
GTEx ID ENSG00000137492

Orthologous Gene

Mouse[2]  NM_028410
Rat [0]  

Chromosomal Region

11q13.5  [76,061,000  -  76,092,015]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1677563
8576172
9447982
9819435
10542257
11555640
12384512
12477932
14695705
14702039
15489334
18029348
20588308
20628624
21139048
21906983
21910972
24255178
24778252

Gene Ontology  (GO ID)

Biological Process

GO:0008285  negative regulation of cell proliferation
GO:0006950  response to stress
GO:0007165  signal transduction

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0046872  metal ion binding
GO:0046983  protein dimerization activity