cytotoxic and regulatory T cell molecule

 jump to detail

Synonym

CRTAM, cytotoxic and regulatory T cell molecule

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:88.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:10.10 peripheral blood:36.40 spleen:37.80 thymus:12.90 bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:2.77 cerebellum:8.79 brain stem:3.50 corpus callosum/glia:2.73 pineal gland:- peripheral nerve:2.84 spine:2.77 retina:- eye:- artery/aorta:2.73 vein:2.77 lymphnode:3.42 peripheral blood:- spleen:4.39 thymus:4 bone marrow:3.10 adipose:2.79 bone:- skin:2.89
CAGE cerebrum:0.84 cerebellum:- brain stem:1.01 corpus callosum/glia:0.13 pineal gland:0.21 peripheral nerve:- spine:0.09 retina:- eye:- artery/aorta:0.87 vein:1.23 lymphnode:1.63 peripheral blood:- spleen:1.50 thymus:2.04 bone marrow:- adipose:1.29 bone:- skin:-
RNA-seq cerebrum:0.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.56 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:19.60    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:2.82 placenta:2.82 prostate:2.74 ovary:2.75 testis:2.68 heart:2.67 muscle:2.72 esophagus:2.83 stomach:2.83 intestine:2.75 colon:2.72 liver/hepato:3.06 lung:4.05 bladder:- kidney:2.70 pituitary:2.67 thyroid/parathyroid:2.86 adrenal gland:2.77 pancreas:2.73 breast:2.77 salivary:2.68
CAGE uterus:0.55 placenta:0.37 prostate:0.53 ovary:0.32 testis:0.28 heart:0.18 muscle:0.05 esophagus:0.52 stomach:- intestine:1.02 colon:0.12     liver/hepato:0.14    lung:2.02 bladder:1.21 kidney:0.21 pituitary:0 thyroid/parathyroid:0.23 adrenal gland:- pancreas:0 breast:0.55 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.15 ovary:0.26 testis:0.33 heart:0.07 muscle:0 esophagus:- stomach:- intestine:- colon:0.06     liver/hepato:0        lung:1.22    bladder:- kidney:0.11 pituitary:- thyroid/parathyroid:0.04 adrenal gland:0.95 pancreas:- breast:0.20 salivary:-

Gene Information

IDs

Refseq ID NM_019604
Gene ID 56253
Unigene ID Hs.159523
Probe set ID 206914_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000109943
GTEx ID ENSG00000109943

Orthologous Gene

Mouse[1]  NM_019465
Rat[1]  NM_001106813

Chromosomal Region

11q24.1  [122,709,208  -  122,743,347]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10811014
12477932
15781451
15811952
16300832
17207965
18329370
19695707
20556794
22051697
23530148
23827383
23871486

Gene Ontology  (GO ID)

Biological Process

GO:0050798  activated T cell proliferation
GO:0008037  cell recognition
GO:0051606  detection of stimulus
GO:0002355  detection of tumor cell
GO:0050715  positive regulation of cytokine secretion
GO:0045954  positive regulation of natural killer cell mediated cytotoxicity
GO:0002860  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0050776  regulation of immune response
GO:0001913  T cell mediated cytotoxicity

Cellular Component

GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005102  receptor binding