proline rich Gla (G-carboxyglutamic acid) 1

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Synonym

Proline-rich Gla protein 1, PRRG1, proline rich Gla (G-carboxyglutamic acid) 1, Proline-rich gamma-carboxyglutamic acid protein 1, PRGP1, TMG1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:87.70 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:60 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:33.60
GeneChip cerebrum:6.90 cerebellum:5.24 brain stem:7.33 corpus callosum/glia:8.57 pineal gland:- peripheral nerve:6.28 spine:8.23 retina:- eye:- artery/aorta:5.26 vein:5.37 lymphnode:4.67 peripheral blood:- spleen:4.87 thymus:4.25 bone marrow:4.19 adipose:5.51 bone:- skin:5.14
CAGE cerebrum:3.96 cerebellum:- brain stem:4.77 corpus callosum/glia:5.08 pineal gland:2.57 peripheral nerve:- spine:5.00 retina:- eye:- artery/aorta:2.74 vein:2.16 lymphnode:1.95 peripheral blood:- spleen:2.78 thymus:0.71 bone marrow:- adipose:3.62 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:76.50 prostate:11.30 ovary:- testis:8.70 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:33.90     liver/hepato:52.80        lung:34.20    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.43 placenta:6.77 prostate:5.01 ovary:5.11 testis:4.32 heart:5.77 muscle:6.76 esophagus:4.78 stomach:4.87 intestine:5.21 colon:4.85 liver/hepato:5.09 lung:5.83 bladder:- kidney:6.11 pituitary:4.28 thyroid/parathyroid:5.50 adrenal gland:5.20 pancreas:4.65 breast:5.30 salivary:4.71
CAGE uterus:3.04 placenta:3.70 prostate:2.84 ovary:2.62 testis:2.41 heart:3.16 muscle:3.67 esophagus:2.82 stomach:- intestine:2.75 colon:2.57     liver/hepato:2.68    lung:3.08 bladder:3.09 kidney:3.41 pituitary:2.21 thyroid/parathyroid:3.14 adrenal gland:- pancreas:1.21 breast:3.09 salivary:2.66
RNA-seq uterus:- placenta:- prostate:0.26 ovary:0.40 testis:0.00 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0.47     liver/hepato:0.36        lung:0.57    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.69 adrenal gland:0.00 pancreas:- breast:0.28 salivary:-

Gene Information

IDs

Refseq ID NM_000950
Gene ID 5638
Unigene ID Hs.190341
Probe set ID 205618_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130962
GTEx ID ENSG00000130962

Orthologous Gene

Mouse[2]  NM_001164275, NM_027322
Rat [0]  

Chromosomal Region

Xp21.1  [37,208,528  -  37,316,548]

Gene Family (Interpro ID)

IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain

Link to Pubmed  (Pubmed ID)

9256434
12477932
15489334
15772651
16344560
16712791
17207965
19322201
19953087
21890473
23940030

Gene Ontology  (GO ID)

Cellular Component

GO:0005576  extracellular region
GO:0005887  integral to plasma membrane

Molecular Function

GO:0005509  calcium ion binding