HtrA serine peptidase 1

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Synonym

HTRA, PRSS11, IGFBP5-protease, HTRA1, HtrA serine peptidase 1, ORF480, Serine protease HTRA1 precursor, HtrA, L56

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:116.10

cerebellum:12.60

brain stem:-

corpus callosum/glia:29.20

pineal gland:296.70

peripheral nerve:153.40

spine:-

retina:118.60

eye:205.70

artery/aorta:-

vein:533.20

lymphnode:-

peripheral blood:36.40

spleen:18.90

thymus:-

bone marrow:39.40

adipose:40.30

bone:409.40

skin:115.20

GeneChip

cerebrum:9.60

cerebellum:8.17

brain stem:9.54

corpus callosum/glia:9.95

pineal gland:-

peripheral nerve:9.59

spine:9.64

retina:-

eye:-

artery/aorta:9.47

vein:9.08

lymphnode:7.22

peripheral blood:-

spleen:7.41

thymus:6.17

bone marrow:5.65

adipose:9.15

bone:-

skin:8.54

CAGE

cerebrum:5.04

cerebellum:-

brain stem:5.31

corpus callosum/glia:5.56

pineal gland:4.97

peripheral nerve:-

spine:4.97

retina:-

eye:-

artery/aorta:5.60

vein:4.02

lymphnode:3.01

peripheral blood:-

spleen:2.97

thymus:2.08

bone marrow:-

adipose:4.76

bone:-

skin:-

RNA-seq

cerebrum:6.94

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.75

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:5.98

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:127.60

placenta:477.20

prostate:67.60

ovary:372.60

testis:4.30

heart:319.30

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:25.40

liver/hepato:-

lung:44

bladder:-

kidney:72.80

pituitary:695.90

thyroid/parathyroid:327.50

adrenal gland:50.80

pancreas:88.90

breast:139.40

salivary:-

GeneChip

uterus:9.08

placenta:10.89

prostate:7.60

ovary:9.42

testis:6.68

heart:8.18

muscle:6.53

esophagus:7.67

stomach:8.35

intestine:7.98

colon:8.16

liver/hepato:7.87

lung:7.79

bladder:-

kidney:8.71

pituitary:9.49

thyroid/parathyroid:7.94

adrenal gland:7.90

pancreas:7.03

breast:9.46

salivary:7.55

CAGE

uterus:4.51

placenta:6.10

prostate:4.48

ovary:5.31

testis:3.49

heart:4.04

muscle:2.30

esophagus:4.08

stomach:-

intestine:2.98

colon:3.83

liver/hepato:5.38

lung:3.49

bladder:4.22

kidney:3.83

pituitary:4.49

thyroid/parathyroid:3.35

adrenal gland:-

pancreas:3.96

breast:5.19

salivary:3.32

RNA-seq

uterus:-

placenta:-

prostate:6.73

ovary:7.65

testis:5.74

heart:4.13

muscle:3.51

esophagus:-

stomach:-

intestine:-

colon:6.04

liver/hepato:7.05

lung:4.70

bladder:-

kidney:5.63

pituitary:-

thyroid/parathyroid:4.78

adrenal gland:5.66

pancreas:-

breast:6.97

salivary:-

IDs

Refseq ID	NM_002775
Gene ID	5654
Unigene ID	Hs.501280
Probe set ID	201185_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000166033
GTEx ID	ENSG00000166033

Orthologous Gene

Mouse[2]	NM_019564
Rat[1]	NM_031721

Chromosomal Region

10q26.13 [124,221,041 - 124,274,424]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001940	Peptidase S1C, HrtA/DegP2/Q/S
IPR002350	Proteinase inhibitor I1, Kazal

GO:0030514	negative regulation of BMP signaling pathway
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0006508	proteolysis
GO:0001558	regulation of cell growth

GO:0005829	cytosol
GO:0031012	extracellular matrix
GO:0005615	extracellular space

GO:0005520	insulin-like growth factor binding
GO:0004252	serine-type endopeptidase activity
GO:0008236	serine-type peptidase activity

HtrA serine peptidase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function