azurocidin 1

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Synonym

azurocidin 1 (cationic antimicrobial protein 37), NAZC, Cationic antimicrobial protein CAP37, HUMAZUR, Heparin-binding protein, AZU, CAP37, AZU1, Azurocidin precursor, AZAMP

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:145.70 spleen:- thymus:- bone marrow:275.50 adipose:- bone:38.40 skin:-
GeneChip cerebrum:3.92 cerebellum:3.87 brain stem:3.90 corpus callosum/glia:3.79 pineal gland:- peripheral nerve:3.65 spine:3.78 retina:- eye:- artery/aorta:3.95 vein:4.17 lymphnode:4.01 peripheral blood:- spleen:3.91 thymus:4.58 bone marrow:11.12 adipose:3.98 bone:- skin:4.08
CAGE cerebrum:0.10 cerebellum:- brain stem:0.10 corpus callosum/glia:0.76 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.69 vein:1.17 lymphnode:0.15 peripheral blood:- spleen:2.15 thymus:2.93 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:0.08 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.02 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.73 placenta:3.64 prostate:3.65 ovary:3.97 testis:3.94 heart:3.81 muscle:3.96 esophagus:4.02 stomach:3.76 intestine:3.85 colon:5.22 liver/hepato:3.75 lung:4.30 bladder:- kidney:3.97 pituitary:3.79 thyroid/parathyroid:3.71 adrenal gland:3.96 pancreas:4.11 breast:3.94 salivary:4.03
CAGE uterus:0.09 placenta:1.55 prostate:0 ovary:0.52 testis:0 heart:1.60 muscle:0.72 esophagus:0.26 stomach:- intestine:0 colon:0.04     liver/hepato:0.78    lung:2.11 bladder:0.26 kidney:0.21 pituitary:0.38 thyroid/parathyroid:0.85 adrenal gland:- pancreas:0 breast:0.55 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.04 ovary:0.10 testis:1.07 heart:0.01 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.20        lung:4.26    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.07 adrenal gland:0.16 pancreas:- breast:0.05 salivary:-

Gene Information

IDs

Refseq ID NM_001700
Gene ID 566
Unigene ID Hs.72885
Probe set ID 214575_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000172232
GTEx ID ENSG00000172232

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

19p13.3  [825,097  -  832,017]

Gene Family (Interpro ID)

IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR009003  Serine/cysteine peptidase, trypsin-like

Link to Pubmed  (Pubmed ID)

1518849
1755383
1897955
1919011
2026172
2049091
2226832
2312733
2332502
2404977
2406527
2501794
8506327
8621683
9095193
9761855
10510329
10534120
10572086
11170199
11861296
11891183
11980855
11994286
12054586
12135665
12351811
12438368
12465046
12477932
12678126
12826073
14515154
15020208
15057824
15304323
15489334
15879141
17207965
18346022
18624398
18787642
19056867
19151333
19590686
20056178
20083497
20107486
20399025
22145905
22207392
22278372

Gene Ontology  (GO ID)

Biological Process

GO:0007205  activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0045123  cellular extravasation
GO:0050829  defense response to Gram-negative bacterium
GO:0008347  glial cell migration
GO:0050930  induction of positive chemotaxis
GO:0006954  inflammatory response
GO:0048246  macrophage chemotaxis
GO:0001774  microglial cell activation
GO:0042117  monocyte activation
GO:0043066  negative regulation of apoptosis
GO:0045785  positive regulation of cell adhesion
GO:0050754  positive regulation of fractalkine biosynthetic process
GO:0050725  positive regulation of interleukin-1 beta biosynthetic process
GO:0045348  positive regulation of MHC class II biosynthetic process
GO:0050766  positive regulation of phagocytosis
GO:0042535  positive regulation of tumor necrosis factor biosynthetic process
GO:0006508  proteolysis
GO:0043114  regulation of vascular permeability

Cellular Component

GO:0042582  azurophil granule
GO:0005576  extracellular region

Molecular Function

GO:0008201  heparin binding
GO:0004252  serine-type endopeptidase activity
GO:0015643  toxin binding