proteasome (prosome, macropain) subunit, alpha type, 3

Synonym

Macropain subunit C8, MGC32631, HC8, Proteasome component C8, PSC3, PSC8, MGC12306, Proteasome subunit alpha type 3, Multicatalytic endopeptidase complex subunit C8, PSMA3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:61.60

cerebellum:37.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:122.70

spine:-

retina:118.60

eye:117.50

artery/aorta:119.90

vein:-

lymphnode:192.10

peripheral blood:72.90

spleen:-

thymus:51.50

bone marrow:118.10

adipose:80.70

bone:89.60

skin:129.60

GeneChip

cerebrum:7.37

cerebellum:7.58

brain stem:7.61

corpus callosum/glia:7.33

pineal gland:-

peripheral nerve:7.89

spine:7.59

retina:-

eye:-

artery/aorta:7.37

vein:7.92

lymphnode:7.91

peripheral blood:-

spleen:8.10

thymus:8.98

bone marrow:7.55

adipose:8.15

bone:-

skin:8.27

CAGE

cerebrum:3.69

cerebellum:-

brain stem:3.75

corpus callosum/glia:3.46

pineal gland:3.86

peripheral nerve:-

spine:3.89

retina:-

eye:-

artery/aorta:3.45

vein:3.41

lymphnode:3.85

peripheral blood:-

spleen:4.05

thymus:3.84

bone marrow:-

adipose:3.86

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:209.60

placenta:72.90

prostate:146.40

ovary:74.50

testis:69.20

heart:89.40

muscle:221

esophagus:-

stomach:169.90

intestine:32.40

colon:237.40

liver/hepato:95

lung:127.10

bladder:-

kidney:62.40

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:257.80

breast:83.60

salivary:-

GeneChip

uterus:8.45

placenta:8.71

prostate:8.50

ovary:8.44

testis:7.80

heart:8.06

muscle:8.54

esophagus:8.56

stomach:7.93

intestine:8.41

colon:7.89

liver/hepato:8.21

lung:8.10

bladder:-

kidney:7.76

pituitary:7.63

thyroid/parathyroid:7.76

adrenal gland:7.96

pancreas:7.90

breast:8.02

salivary:7.57

CAGE

uterus:3.78

placenta:4.38

prostate:3.81

ovary:3.71

testis:3.55

heart:4.21

muscle:4.41

esophagus:3.95

stomach:-

intestine:4.05

colon:3.60

liver/hepato:4.45

lung:3.91

bladder:4.01

kidney:4.43

pituitary:4.02

thyroid/parathyroid:4.10

adrenal gland:-

pancreas:3.40

breast:3.52

salivary:3.87

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.00

testis:0.80

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.38

lung:0.00

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_152132
Gene ID	5684
Unigene ID	Hs.558799
Probe set ID	201532_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000100567
GTEx ID	ENSG00000100567

Orthologous Gene

Mouse[1]	NM_011184
Rat [0]

Chromosomal Region

14q23.1 [58,711,549 - 58,738,730]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0006915	apoptosis
GO:0034641	cellular nitrogen compound metabolic process
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0000082	G1/S transition of mitotic cell cycle
GO:0010467	gene expression
GO:0000278	mitotic cell cycle
GO:0016071	mRNA metabolic process
GO:0043066	negative regulation of apoptosis
GO:0051436	negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0051437	positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0000209	protein polyubiquitination
GO:0042981	regulation of apoptosis
GO:0006521	regulation of cellular amino acid metabolic process
GO:0051439	regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0016070	RNA metabolic process
GO:0016032	viral reproduction
GO:0019048	virus-host interaction

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0000502	proteasome complex
GO:0005839	proteasome core complex
GO:0019773	proteasome core complex, alpha-subunit complex

Molecular Function

GO:0005515	protein binding
GO:0004298	threonine-type endopeptidase activity

proteasome (prosome, macropain) subunit, alpha type, 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function