SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1

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Synonym

hHEL1, ATP-dependent helicase 1, SMARCAD1, KIAA1122, ETL1, DKFZP762K2015, DKFZp762K2015

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:53.30 cerebellum:63 brain stem:- corpus callosum/glia:- pineal gland:296.70 peripheral nerve:61.30 spine:- retina:118.60 eye:11.80 artery/aorta:89.90 vein:133.30 lymphnode:70.80 peripheral blood:18.20 spleen:- thymus:25.80 bone marrow:- adipose:40.30 bone:12.80 skin:33.60
GeneChip nodata
CAGE cerebrum:3.42 cerebellum:- brain stem:3.35 corpus callosum/glia:2.86 pineal gland:3.57 peripheral nerve:- spine:3.71 retina:- eye:- artery/aorta:2.88 vein:3.40 lymphnode:3.23 peripheral blood:- spleen:3.36 thymus:4.05 bone marrow:- adipose:3.00 bone:- skin:-
RNA-seq cerebrum:1.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.36 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:25.50 prostate:22.50 ovary:- testis:69.20 heart:38.30 muscle:60.30 esophagus:- stomach:21.20 intestine:32.40 colon:17     liver/hepato:-        lung:34.20    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:37.20 salivary:-
GeneChip nodata
CAGE uterus:3.42 placenta:3.10 prostate:3.22 ovary:3.02 testis:3.40 heart:3.09 muscle:2.65 esophagus:3.08 stomach:- intestine:3.07 colon:3.16     liver/hepato:3.09    lung:3.31 bladder:3.03 kidney:3.31 pituitary:4.07 thyroid/parathyroid:3.17 adrenal gland:- pancreas:2.90 breast:3.43 salivary:2.35
RNA-seq uterus:- placenta:- prostate:1.27 ovary:0.89 testis:1.79 heart:0.41 muscle:0.10 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.20    bladder:- kidney:0.55 pituitary:- thyroid/parathyroid:1.66 adrenal gland:0.21 pancreas:- breast:0.75 salivary:-

Gene Information

IDs

Refseq ID NM_020159
Gene ID 56916
Unigene ID Hs.410406
Probe set ID -
Ensembl ID ENSG00000163104
GTEx ID ENSG00000163104

Orthologous Gene

Mouse[2]  NM_007958
Rat[1]  NM_001107864

Chromosomal Region

4q22.3  [95,128,762  -  95,212,443]

Gene Family (Interpro ID)

IPR014001  DEAD-like helicase, N-terminal
IPR014021  Helicase, superfamily 1/2, ATP-binding domain

Link to Pubmed  (Pubmed ID)

10574461
11031099
12477932
14702039
15302935
15489334
16344560
17081983
18029348
18675275
19471022
20508149
20889312
21139048
21252943
21549307
21693764
21820097
21890473
21906983
22101266
22505724
22863883
22864933
22960744
23000965
23666239
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0043044  ATP-dependent chromatin remodeling
GO:0016568  chromatin modification
GO:0006338  chromatin remodeling
GO:0051304  chromosome separation
GO:0000729  DNA double-strand break processing
GO:0070932  histone H3 deacetylation
GO:0070933  histone H4 deacetylation
GO:0009117  nucleotide metabolic process
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051260  protein homooligomerization
GO:0000018  regulation of DNA recombination

Cellular Component

GO:0000792  heterochromatin
GO:0016363  nuclear matrix
GO:0043596  nuclear replication fork
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0003677  DNA binding
GO:0004386  helicase activity
GO:0003676  nucleic acid binding
GO:0005515  protein binding