proteasome (prosome, macropain) subunit, beta type, 4

jump to detail

Synonym

HsN3, Proteasome chain 3, Multicatalytic endopeptidase complex beta chain, Macropain beta chain, HsBPROS26, HSN3, Proteasome subunit beta type 4 precursor, Proteasome beta chain, HN3, PROS26, PSMB4

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:75.80 cerebellum:50.40 brain stem:- corpus callosum/glia:87.50 pineal gland:445 peripheral nerve:245.40 spine:- retina:474.60 eye:252.70 artery/aorta:329.70 vein:199.90 lymphnode:151.70 peripheral blood:200.40 spleen:170.20 thymus:206.10 bone marrow:78.70 adipose:121 bone:89.60 skin:86.40
GeneChip cerebrum:8.54 cerebellum:8.21 brain stem:8.92 corpus callosum/glia:8.07 pineal gland:- peripheral nerve:8.74 spine:8.37 retina:- eye:- artery/aorta:8.83 vein:8.53 lymphnode:8.71 peripheral blood:- spleen:8.65 thymus:9.14 bone marrow:8.24 adipose:8.77 bone:- skin:9.19
CAGE cerebrum:4.07 cerebellum:- brain stem:3.76 corpus callosum/glia:3.58 pineal gland:4.01 peripheral nerve:- spine:4.21 retina:- eye:- artery/aorta:4.66 vein:4.34 lymphnode:4.23 peripheral blood:- spleen:3.72 thymus:3.98 bone marrow:- adipose:3.79 bone:- skin:-
RNA-seq cerebrum:5.93 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.57 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.53 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:211.30 prostate:90.10 ovary:- testis:69.20 heart:204.30 muscle:80.40 esophagus:- stomach:42.50 intestine:97.20 colon:76.30     liver/hepato:126.70        lung:190.60    bladder:125.60 kidney:72.80 pituitary:232 thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:284.50 breast:111.50 salivary:328.40
GeneChip uterus:8.96 placenta:8.31 prostate:9.44 ovary:8.98 testis:8.19 heart:8.47 muscle:8.83 esophagus:8.59 stomach:8.41 intestine:8.62 colon:8.50 liver/hepato:8.72 lung:8.54 bladder:- kidney:8.80 pituitary:8.77 thyroid/parathyroid:8.75 adrenal gland:8.88 pancreas:8.28 breast:8.90 salivary:8.67
CAGE uterus:3.91 placenta:3.92 prostate:3.98 ovary:3.74 testis:3.81 heart:4.17 muscle:4.31 esophagus:4.22 stomach:- intestine:3.87 colon:4.25     liver/hepato:4.27    lung:3.98 bladder:4.29 kidney:4.20 pituitary:4.11 thyroid/parathyroid:3.97 adrenal gland:- pancreas:4.56 breast:4.28 salivary:3.82
RNA-seq uterus:- placenta:- prostate:6.95 ovary:6.68 testis:6.37 heart:5.83 muscle:6.29 esophagus:- stomach:- intestine:- colon:6.32     liver/hepato:6.84        lung:6.55    bladder:- kidney:6.97 pituitary:- thyroid/parathyroid:6.54 adrenal gland:6.74 pancreas:- breast:6.52 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0006915  apoptosis
GO:0034641  cellular nitrogen compound metabolic process
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0000082  G1/S transition of mitotic cell cycle
GO:0010467  gene expression
GO:0000278  mitotic cell cycle
GO:0016071  mRNA metabolic process
GO:0043066  negative regulation of apoptosis
GO:0002862  negative regulation of inflammatory response to antigenic stimulus
GO:0051436  negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0051437  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0000209  protein polyubiquitination
GO:0042981  regulation of apoptosis
GO:0006521  regulation of cellular amino acid metabolic process
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0016070  RNA metabolic process
GO:0016032  viral reproduction
GO:0019048  virus-host interaction

Cellular Component

GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0000502  proteasome complex
GO:0005839  proteasome core complex

Molecular Function

GO:0001530  lipopolysaccharide binding
GO:0004298  threonine-type endopeptidase activity