proteasome (prosome, macropain) assembly chaperone 2

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Synonym

PAC2, MGC15092, MDS003, TNFSF5IP1, HCCA3, HsT1707, CLAST3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:32 cerebellum:63 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:29.40 artery/aorta:- vein:- lymphnode:- peripheral blood:36.40 spleen:- thymus:- bone marrow:98.40 adipose:40.30 bone:38.40 skin:19.20
GeneChip cerebrum:7.93 cerebellum:8.22 brain stem:8.03 corpus callosum/glia:8.08 pineal gland:- peripheral nerve:8.31 spine:8.16 retina:- eye:- artery/aorta:8.49 vein:8.67 lymphnode:8.80 peripheral blood:- spleen:8.64 thymus:9.29 bone marrow:8.48 adipose:8.85 bone:- skin:8.95
CAGE cerebrum:3.45 cerebellum:- brain stem:3.38 corpus callosum/glia:3.47 pineal gland:3.27 peripheral nerve:- spine:3.57 retina:- eye:- artery/aorta:3.93 vein:3.86 lymphnode:3.96 peripheral blood:- spleen:3.80 thymus:3.97 bone marrow:- adipose:3.91 bone:- skin:-
RNA-seq cerebrum:2.17 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.34 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.96 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:40.10 prostate:56.30 ovary:37.30 testis:64.90 heart:25.50 muscle:60.30 esophagus:- stomach:106.20 intestine:- colon:8.50     liver/hepato:52.80        lung:29.30    bladder:- kidney:62.40 pituitary:116 thyroid/parathyroid:327.50 adrenal gland:- pancreas:53.30 breast:9.30 salivary:-
GeneChip uterus:9.08 placenta:8.36 prostate:9.02 ovary:9.23 testis:10.12 heart:8.26 muscle:7.94 esophagus:9.04 stomach:8.52 intestine:8.66 colon:8.81 liver/hepato:8.15 lung:8.68 bladder:- kidney:8.48 pituitary:8.09 thyroid/parathyroid:8.67 adrenal gland:8.48 pancreas:8.67 breast:8.88 salivary:8.25
CAGE uterus:3.76 placenta:3.74 prostate:3.80 ovary:3.83 testis:4.71 heart:3.51 muscle:3.38 esophagus:4.03 stomach:- intestine:3.76 colon:3.87     liver/hepato:3.91    lung:3.75 bladder:3.89 kidney:3.86 pituitary:3.44 thyroid/parathyroid:3.87 adrenal gland:- pancreas:3.89 breast:3.81 salivary:3.82
RNA-seq uterus:- placenta:- prostate:4.80 ovary:3.82 testis:5.19 heart:3.07 muscle:4.50 esophagus:- stomach:- intestine:- colon:3.94     liver/hepato:3.15        lung:4.00    bladder:- kidney:2.97 pituitary:- thyroid/parathyroid:3.74 adrenal gland:3.93 pancreas:- breast:4.00 salivary:-

Gene Information

IDs

Refseq ID NM_020232
Gene ID 56984
Unigene ID Hs.464652
Probe set ID 218467_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000128789
GTEx ID ENSG00000128789

Orthologous Gene

Mouse[2]  NM_134138
Rat[1]  NM_001106138

Chromosomal Region

18p11.21  [12,702,425  -  12,725,739]

Gene Family (Interpro ID)

IPR019151  Proteasome assembly chaperone 2
IPR016562  Proteasome assembly chaperone 2, eukaryotic

Link to Pubmed  (Pubmed ID)

8125298
11854909
12147697
12477932
14702039
16169070
16251969
17189198
17207965
17554260
17554300
17948026
18174230
18978792
19193609
19738201
21139048
21890473
21906983
21963094
22053931
22939629
23000965
24811749

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007094  mitotic cell cycle spindle assembly checkpoint
GO:0043248  proteasome assembly
GO:0042981  regulation of apoptosis

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding