solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7

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Synonym

VGLUT1, SLC17A7, BNPI

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:141 cerebellum:50.40 brain stem:- corpus callosum/glia:- pineal gland:741.70 peripheral nerve:- spine:- retina:118.60 eye:182.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.97 cerebellum:9.55 brain stem:7.29 corpus callosum/glia:6.50 pineal gland:- peripheral nerve:7.53 spine:5.97 retina:- eye:- artery/aorta:6.12 vein:6.36 lymphnode:5.91 peripheral blood:- spleen:5.85 thymus:6.11 bone marrow:6.36 adipose:6.25 bone:- skin:6.02
CAGE cerebrum:3.97 cerebellum:- brain stem:2.68 corpus callosum/glia:3.04 pineal gland:6.15 peripheral nerve:- spine:0.17 retina:- eye:- artery/aorta:1.61 vein:1.03 lymphnode:0.56 peripheral blood:- spleen:0 thymus:0.12 bone marrow:- adipose:1.25 bone:- skin:-
RNA-seq cerebrum:6.86 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.06 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.50 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:37.30 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.93 placenta:5.84 prostate:5.76 ovary:6 testis:6.03 heart:6.20 muscle:6.20 esophagus:5.97 stomach:6.17 intestine:6.15 colon:6.40 liver/hepato:6.09 lung:5.96 bladder:- kidney:6.09 pituitary:6.26 thyroid/parathyroid:6.08 adrenal gland:6.07 pancreas:6.24 breast:6.19 salivary:6.07
CAGE uterus:0.74 placenta:0.16 prostate:0.70 ovary:0.26 testis:0.79 heart:0.87 muscle:0.67 esophagus:1.17 stomach:- intestine:0.53 colon:0.93     liver/hepato:0    lung:0.35 bladder:1.06 kidney:0.27 pituitary:0 thyroid/parathyroid:0.90 adrenal gland:- pancreas:0.58 breast:0.90 salivary:0.36
RNA-seq uterus:- placenta:- prostate:1.18 ovary:0.18 testis:1.23 heart:0.54 muscle:0.76 esophagus:- stomach:- intestine:- colon:1.38     liver/hepato:0.03        lung:0.31    bladder:- kidney:0.01 pituitary:- thyroid/parathyroid:0.71 adrenal gland:1.36 pancreas:- breast:1.27 salivary:-

Gene Information

IDs

Refseq ID NM_020309
Gene ID 57030
Unigene ID Hs.375616
Probe set ID 204229_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000104888
GTEx ID ENSG00000104888

Orthologous Gene

Mouse[1]  NM_182993
Rat[1]  NM_053859

Chromosomal Region

19q13.33  [49,932,656  -  49,945,617]

Gene Family (Interpro ID)

IPR020846  Major facilitator superfamily
IPR016196  Major facilitator superfamily, general substrate transporter

Link to Pubmed  (Pubmed ID)

8632143
8889548
10820226
10938000
11001057
12107411
12477932
14702039
15653259
15961236
16606361
17531353
17660252
18155679
19086053
19156168
19720501
19839996
21396926
22510271
23022470

Gene Ontology  (GO ID)

Biological Process

GO:0014047  glutamate secretion
GO:0006811  ion transport
GO:0051938  L-glutamate import
GO:0007616  long-term memory
GO:0007269  neurotransmitter secretion
GO:0006817  phosphate transport
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0042137  sequestering of neurotransmitter
GO:0007268  synaptic transmission
GO:0035249  synaptic transmission, glutamatergic
GO:0055085  transmembrane transport

Cellular Component

GO:0030054  cell junction
GO:0060203  clathrin sculpted glutamate transport vesicle membrane
GO:0060076  excitatory synapse
GO:0016021  integral to membrane
GO:0043005  neuron projection
GO:0005886  plasma membrane
GO:0048786  presynaptic active zone
GO:0030672  synaptic vesicle membrane

Molecular Function

GO:0005315  inorganic phosphate transmembrane transporter activity
GO:0005313  L-glutamate transmembrane transporter activity
GO:0015321  sodium-dependent phosphate transmembrane transporter activity
GO:0015319  sodium:inorganic phosphate symporter activity