proteasome (prosome, macropain) 26S subunit, non-ATPase, 2

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Synonym

PSMD2, MGC14274, 26S proteasome regulatory subunit S2, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome subunit p97, S2, 26S proteasome regulatory subunit RPN1, TRAP2, 55.11 protein, P97

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:180.10 cerebellum:188.90 brain stem:- corpus callosum/glia:320.80 pineal gland:296.70 peripheral nerve:184 spine:449.20 retina:118.60 eye:211.60 artery/aorta:179.90 vein:333.20 lymphnode:262.90 peripheral blood:273.30 spleen:94.50 thymus:77.30 bone marrow:39.40 adipose:363 bone:191.90 skin:192
GeneChip cerebrum:8.45 cerebellum:8.39 brain stem:8.88 corpus callosum/glia:8.02 pineal gland:- peripheral nerve:8.83 spine:8.12 retina:- eye:- artery/aorta:8.31 vein:8.19 lymphnode:8.28 peripheral blood:- spleen:7.83 thymus:8.49 bone marrow:8.18 adipose:8.30 bone:- skin:8.77
CAGE cerebrum:4.07 cerebellum:- brain stem:3.94 corpus callosum/glia:3.82 pineal gland:4.10 peripheral nerve:- spine:3.88 retina:- eye:- artery/aorta:3.66 vein:3.61 lymphnode:3.80 peripheral blood:- spleen:3.79 thymus:3.70 bone marrow:- adipose:3.63 bone:- skin:-
RNA-seq cerebrum:4.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.83 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.17 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:127.60 placenta:102 prostate:78.90 ovary:149.10 testis:398 heart:153.30 muscle:160.70 esophagus:- stomach:63.70 intestine:64.80 colon:118.70     liver/hepato:52.80        lung:83.10    bladder:- kidney:156 pituitary:116 thyroid/parathyroid:- adrenal gland:304.70 pancreas:106.70 breast:269.50 salivary:328.40
GeneChip uterus:8.32 placenta:7.94 prostate:8.53 ovary:8.32 testis:9.57 heart:8.28 muscle:9.40 esophagus:8.84 stomach:7.91 intestine:8.19 colon:8.25 liver/hepato:7.90 lung:8.21 bladder:- kidney:8.14 pituitary:8.28 thyroid/parathyroid:8.27 adrenal gland:8.40 pancreas:7.41 breast:8.42 salivary:7.87
CAGE uterus:3.56 placenta:3.98 prostate:3.68 ovary:3.59 testis:4.22 heart:4.30 muscle:5.26 esophagus:3.78 stomach:- intestine:3.41 colon:3.54     liver/hepato:3.99    lung:3.36 bladder:3.61 kidney:3.81 pituitary:3.57 thyroid/parathyroid:3.62 adrenal gland:- pancreas:3.65 breast:3.52 salivary:3.77
RNA-seq uterus:- placenta:- prostate:5.00 ovary:5.21 testis:5.87 heart:5.07 muscle:7.08 esophagus:- stomach:- intestine:- colon:4.92     liver/hepato:4.73        lung:4.59    bladder:- kidney:5.20 pituitary:- thyroid/parathyroid:5.58 adrenal gland:4.86 pancreas:- breast:5.16 salivary:-

IDs

Refseq ID NM_002808
Gene ID 5708
Unigene ID Hs.518464
Probe set ID 200830_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000175166
GTEx ID ENSG00000175166

Orthologous Gene

Mouse[2]  NM_134101
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0006915  apoptosis
GO:0034641  cellular nitrogen compound metabolic process
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0000082  G1/S transition of mitotic cell cycle
GO:0010467  gene expression
GO:0000278  mitotic cell cycle
GO:0016071  mRNA metabolic process
GO:0043066  negative regulation of apoptosis
GO:0051436  negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0051437  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0000209  protein polyubiquitination
GO:0042981  regulation of apoptosis
GO:0006521  regulation of cellular amino acid metabolic process
GO:0042176  regulation of protein catabolic process
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0016070  RNA metabolic process
GO:0016032  viral reproduction

Cellular Component

GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0022624  proteasome accessory complex
GO:0000502  proteasome complex
GO:0005838  proteasome regulatory particle

Molecular Function

GO:0030234  enzyme regulator activity
GO:0005515  protein binding