pellino homolog 1 (Drosophila)

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Synonym

pellino (Drosophila) homolog 1, MGC50990, pellino homolog 1 (Drosophila), Protein pellino homolog 1, PRISM, Pellino-related intracellular signaling molecule, PELI1, Pellino-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:98.40 cerebellum:113.30 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:184 spine:336.90 retina:- eye:58.80 artery/aorta:30 vein:- lymphnode:222.40 peripheral blood:54.70 spleen:- thymus:116 bone marrow:59 adipose:80.70 bone:64 skin:48
GeneChip cerebrum:6.18 cerebellum:5.99 brain stem:5.95 corpus callosum/glia:6.71 pineal gland:- peripheral nerve:7.40 spine:6.96 retina:- eye:- artery/aorta:6.83 vein:7.32 lymphnode:7.35 peripheral blood:- spleen:7.07 thymus:7.82 bone marrow:7.33 adipose:7 bone:- skin:7.83
CAGE cerebrum:2.97 cerebellum:- brain stem:3.12 corpus callosum/glia:3.15 pineal gland:2.35 peripheral nerve:- spine:3.49 retina:- eye:- artery/aorta:3.40 vein:3.25 lymphnode:3.56 peripheral blood:- spleen:3.60 thymus:3.47 bone marrow:- adipose:3.29 bone:- skin:-
RNA-seq cerebrum:3.51 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.31 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.42 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:65.60 prostate:22.50 ovary:- testis:99.50 heart:38.30 muscle:20.10 esophagus:- stomach:- intestine:- colon:33.90     liver/hepato:21.10        lung:156.40    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:17.80 breast:74.30 salivary:-
GeneChip uterus:7.35 placenta:7.54 prostate:7.30 ovary:6.18 testis:6.61 heart:6.09 muscle:5.42 esophagus:8.33 stomach:6.65 intestine:6.66 colon:6.34 liver/hepato:5.49 lung:7.82 bladder:- kidney:5.50 pituitary:6.53 thyroid/parathyroid:5.54 adrenal gland:5.56 pancreas:4.90 breast:7.42 salivary:6.53
CAGE uterus:3.29 placenta:3.28 prostate:2.80 ovary:2.50 testis:2.85 heart:2.93 muscle:2.32 esophagus:3.75 stomach:- intestine:3.54 colon:3.16     liver/hepato:2.67    lung:3.79 bladder:3.40 kidney:2.61 pituitary:3.28 thyroid/parathyroid:2.21 adrenal gland:- pancreas:2.41 breast:3.83 salivary:2.78
RNA-seq uterus:- placenta:- prostate:3.34 ovary:2.27 testis:3.58 heart:2.01 muscle:1.94 esophagus:- stomach:- intestine:- colon:3.86     liver/hepato:3.21        lung:4.95    bladder:- kidney:3.10 pituitary:- thyroid/parathyroid:2.37 adrenal gland:4.21 pancreas:- breast:4.01 salivary:-

Gene Information

IDs

Refseq ID NM_020651
Gene ID 57162
Unigene ID Hs.7886
Probe set ID 218319_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000197329
GTEx ID ENSG00000197329

Orthologous Gene

Mouse[2]  NM_023324
Rat[1]  NM_001100565

Chromosomal Region

2p14  [64,319,786  -  64,371,588]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11132151
11306823
12477932
12496252
12804775
14702039
15276183
15489334
15917247
16344560
16884718
16951688
17207965
17675297
17997719
18326498
18976975
19081057
19264966
19734906
21120624
21204785
21221998
21890473
22105492
22505724
23602568
23846693
23921680
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0045087  innate immune response
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0042130  negative regulation of T cell proliferation
GO:0030890  positive regulation of B cell proliferation
GO:0001819  positive regulation of cytokine production
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0031398  positive regulation of protein ubiquitination
GO:0034141  positive regulation of toll-like receptor 3 signaling pathway
GO:0034145  positive regulation of toll-like receptor 4 signaling pathway
GO:0070936  protein K48-linked ubiquitination
GO:0043331  response to dsRNA
GO:0032496  response to lipopolysaccharide
GO:0008063  Toll signaling pathway
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0004842  ubiquitin-protein ligase activity