mitochondrial antiviral signaling protein

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Synonym

FLJ27482, FLJ41962, MAVS, Ips-1, DKFZp666M015, VISA, KIAA1271, virus-induced signaling adapter

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:43.90

cerebellum:37.80

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:61.30

spine:224.60

retina:-

eye:105.80

artery/aorta:119.90

vein:133.30

lymphnode:20.20

peripheral blood:72.90

spleen:94.50

thymus:219

bone marrow:98.40

adipose:40.30

bone:51.20

skin:67.20

GeneChip

nodata

CAGE

cerebrum:3.49

cerebellum:-

brain stem:3.58

corpus callosum/glia:3.84

pineal gland:3.10

peripheral nerve:-

spine:3.60

retina:-

eye:-

artery/aorta:3.99

vein:3.71

lymphnode:3.72

peripheral blood:-

spleen:3.38

thymus:3.51

bone marrow:-

adipose:3.69

bone:-

skin:-

RNA-seq

cerebrum:1.76

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.71

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.36

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:136.70

placenta:72.90

prostate:78.90

ovary:186.30

testis:34.60

heart:12.80

muscle:-

esophagus:-

stomach:42.50

intestine:97.20

colon:161.10

liver/hepato:42.20

lung:83.10

bladder:-

kidney:62.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:53.30

breast:185.90

salivary:-

GeneChip

nodata

CAGE

uterus:3.60

placenta:3.43

prostate:3.61

ovary:3.39

testis:3.10

heart:3.75

muscle:4.03

esophagus:3.59

stomach:-

intestine:3.44

colon:3.89

liver/hepato:3.21

lung:3.70

bladder:3.46

kidney:3.24

pituitary:3.63

thyroid/parathyroid:3.50

adrenal gland:-

pancreas:3.93

breast:4.19

salivary:3.66

RNA-seq

uterus:-

placenta:-

prostate:0.97

ovary:3.28

testis:1.85

heart:2.43

muscle:3.99

esophagus:-

stomach:-

intestine:-

colon:2.44

liver/hepato:0.97

lung:1.66

bladder:-

kidney:2.14

pituitary:-

thyroid/parathyroid:3.45

adrenal gland:2.92

pancreas:-

breast:3.06

salivary:-

IDs

Refseq ID	NM_020746
Gene ID	57506
Unigene ID	Hs.570362
Probe set ID	-
Ensembl ID	ENSG00000088888
GTEx ID	ENSG00000088888

Orthologous Gene

Mouse[2]	NM_001206382, NM_001206383, NM_001206385, NM_144888
Rat[1]	NM_001005556, NM_001206383, NM_001206385, NM_144888

Chromosomal Region

20p13 [3,827,487 - 3,849,280]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0002218	activation of innate immune response
GO:0071360	cellular response to exogenous dsRNA
GO:0042742	defense response to bacterium
GO:0051607	defense response to virus
GO:0045087	innate immune response
GO:0032480	negative regulation of type I interferon production
GO:0045071	negative regulation of viral genome replication
GO:0002230	positive regulation of defense response to virus by host
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032727	positive regulation of interferon-alpha production
GO:0032728	positive regulation of interferon-beta production
GO:0032757	positive regulation of interleukin-8 production
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0033160	positive regulation of protein import into nucleus, translocation
GO:0051091	positive regulation of transcription factor activity
GO:0042993	positive regulation of transcription factor import into nucleus
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0032760	positive regulation of tumor necrosis factor production
GO:0060340	positive regulation of type I interferon-mediated signaling pathway
GO:0007165	signal transduction
GO:0019048	virus-host interaction

Cellular Component

GO:0016021	integral to membrane
GO:0031966	mitochondrial membrane
GO:0005741	mitochondrial outer membrane
GO:0005778	peroxisomal membrane

Molecular Function

GO:0050700	CARD domain binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004871	signal transducer activity

mitochondrial antiviral signaling protein

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function