serine incorporator 1

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Synonym

TDE2, UNQ396/PRO732, SERINC1, tumor differentially expressed 2, KIAA1253, serine incorporator 1, TDE1L, Tumor differentially expressed 1 protein-like, Serine incorporator 1, TMS-2, Tumor differentially expressed protein 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1997 cerebellum:2846.20 brain stem:- corpus callosum/glia:2216.30 pineal gland:445 peripheral nerve:276 spine:449.20 retina:118.60 eye:170.40 artery/aorta:389.70 vein:- lymphnode:40.40 peripheral blood:619.40 spleen:737.40 thymus:2048.50 bone marrow:59 adipose:363 bone:1484.20 skin:470.40
GeneChip cerebrum:9.64 cerebellum:9.22 brain stem:10.03 corpus callosum/glia:9.47 pineal gland:- peripheral nerve:9.35 spine:9.94 retina:- eye:- artery/aorta:8.04 vein:8.32 lymphnode:7.57 peripheral blood:- spleen:8.04 thymus:7.99 bone marrow:7.37 adipose:8.59 bone:- skin:8.11
CAGE cerebrum:6.16 cerebellum:- brain stem:6.59 corpus callosum/glia:6.25 pineal gland:6.13 peripheral nerve:- spine:6.53 retina:- eye:- artery/aorta:5.54 vein:4.64 lymphnode:4.72 peripheral blood:- spleen:5.12 thymus:4.53 bone marrow:- adipose:5.76 bone:- skin:-
RNA-seq cerebrum:8.46 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.78 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:692.60 placenta:477.20 prostate:202.80 ovary:149.10 testis:731.20 heart:191.60 muscle:80.40 esophagus:- stomach:276.10 intestine:324 colon:50.90     liver/hepato:179.40        lung:733.10    bladder:753.70 kidney:176.80 pituitary:232 thyroid/parathyroid:163.70 adrenal gland:761.80 pancreas:426.80 breast:148.70 salivary:328.40
GeneChip uterus:8.49 placenta:8.49 prostate:8.97 ovary:8.33 testis:7.31 heart:8.31 muscle:7.88 esophagus:7.62 stomach:7.86 intestine:8.01 colon:7.23 liver/hepato:7.92 lung:8.45 bladder:- kidney:7.89 pituitary:8.36 thyroid/parathyroid:8.52 adrenal gland:8.44 pancreas:7.48 breast:8.23 salivary:7.54
CAGE uterus:5.31 placenta:5.56 prostate:5.32 ovary:5.36 testis:4.76 heart:5.02 muscle:4.83 esophagus:5.31 stomach:- intestine:5.27 colon:4.66     liver/hepato:5.59    lung:5.45 bladder:5.63 kidney:5.54 pituitary:5.54 thyroid/parathyroid:5.52 adrenal gland:- pancreas:4.68 breast:5.36 salivary:4.44
RNA-seq uterus:- placenta:- prostate:7.22 ovary:6.46 testis:6.36 heart:6.33 muscle:6.84 esophagus:- stomach:- intestine:- colon:7.40     liver/hepato:6.35        lung:7.51    bladder:- kidney:6.98 pituitary:- thyroid/parathyroid:7.46 adrenal gland:6.48 pancreas:- breast:7.59 salivary:-

Gene Information

IDs

Refseq ID NM_020755
Gene ID 57515
Unigene ID Hs.146668
Probe set ID 208671_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000111897
GTEx ID ENSG00000111897

Orthologous Gene

Mouse[4]  NM_019760
Rat[1]  NM_182951

Chromosomal Region

6q22.31  [122,764,493  -  122,907,269]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10574462
10637174
10931946
12477932
12975309
14574404
15489334
17081983
17207965
18978678
20195357
21890473
21906983
21963094
21988832
22053931
22939629
23000965
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0015825  L-serine transport
GO:0006658  phosphatidylserine metabolic process
GO:0008654  phospholipid biosynthetic process
GO:0051347  positive regulation of transferase activity
GO:0006665  sphingolipid metabolic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0015194  L-serine transmembrane transporter activity
GO:0005515  protein binding