WD repeat and FYVE domain containing 1

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Synonym

FENS-1, KIAA1435, Phosphoinositide-binding protein 1, WD repeat and FYVE domain containing 1, WD40 and FYVE domain containing 1, Zinc finger FYVE domain-containing protein 17, WD repeat and FYVE domain-containing protein 1, WD40- and FYVE domain-containing protein 1, WDFY1, ZFYVE17, WDF1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:3.49 cerebellum:- brain stem:3.67 corpus callosum/glia:3.72 pineal gland:3.49 peripheral nerve:- spine:3.53 retina:- eye:- artery/aorta:4.04 vein:3.60 lymphnode:3.66 peripheral blood:- spleen:3.77 thymus:3.28 bone marrow:- adipose:4.08 bone:- skin:-
RNA-seq cerebrum:3.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.68 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.30 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:3.89 placenta:3.76 prostate:3.60 ovary:3.81 testis:3.57 heart:3.64 muscle:3.19 esophagus:3.48 stomach:- intestine:3.76 colon:3.74     liver/hepato:3.53    lung:3.86 bladder:3.78 kidney:3.37 pituitary:3.71 thyroid/parathyroid:3.62 adrenal gland:- pancreas:3.42 breast:3.92 salivary:3.24
RNA-seq uterus:- placenta:- prostate:3.80 ovary:4.64 testis:4.04 heart:2.53 muscle:2.72 esophagus:- stomach:- intestine:- colon:3.61     liver/hepato:2.72        lung:4.25    bladder:- kidney:3.60 pituitary:- thyroid/parathyroid:4.06 adrenal gland:3.67 pancreas:- breast:3.62 salivary:-

Gene Information

IDs

Refseq ID NM_020830
Gene ID 57590
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000085449
GTEx ID ENSG00000085449

Orthologous Gene

Mouse[4]  NM_001111279, NM_027057
Rat[1]  NM_001008331, NM_027057

Chromosomal Region

2q36.1  [224,720,433  -  224,810,104]

Gene Family (Interpro ID)

IPR020472  G-protein beta WD-40 repeat, region
IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain
IPR000306  Zinc finger, FYVE-type
IPR011011  Zinc finger, FYVE/PHD-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

10718198
11739631
12477932
14702039
15489334
17207965
19322201
22939629
24654937

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process

Cellular Component

GO:0005829  cytosol
GO:0005769  early endosome
GO:0005634  nucleus

Molecular Function

GO:0005545  phosphatidylinositol binding
GO:0008270  zinc ion binding