solute carrier family 46, member 2

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Synonym

Thymic stromal cotransporter homolog, Ly110, TSCOT, thymic stromal co-transporter

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:36.40 spleen:- thymus:231.90 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0.16 cerebellum:- brain stem:0 corpus callosum/glia:0.07 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:2.71 lymphnode:0.84 peripheral blood:- spleen:0.66 thymus:3.35 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:0.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.16 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:22.50 ovary:- testis:8.70 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:44    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:1.03 placenta:0.24 prostate:0.74 ovary:0.14 testis:0.99 heart:0.04 muscle:0 esophagus:0.33 stomach:- intestine:0.07 colon:0     liver/hepato:0    lung:2.99 bladder:0.69 kidney:0.27 pituitary:0.10 thyroid/parathyroid:0.06 adrenal gland:- pancreas:0 breast:0.55 salivary:0
RNA-seq uterus:- placenta:- prostate:1.21 ovary:0.09 testis:0.54 heart:0.05 muscle:0 esophagus:- stomach:- intestine:- colon:0.01     liver/hepato:0.10        lung:2.36    bladder:- kidney:0.06 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.07 pancreas:- breast:0.23 salivary:-

Gene Information

IDs

Refseq ID NM_033051
Gene ID 57864
Unigene ID Hs.512668
Probe set ID -
Ensembl ID ENSG00000119457
GTEx ID ENSG00000119457

Orthologous Gene

Mouse[1]  NM_021053
Rat[1]  NM_001106652

Chromosomal Region

9q32  [115,641,200  -  115,653,193]

Gene Family (Interpro ID)

IPR020846  Major facilitator superfamily
IPR011701  Major facilitator superfamily MFS-1
IPR016196  Major facilitator superfamily, general substrate transporter
IPR001958  Tetracycline resistance protein, TetA

Link to Pubmed  (Pubmed ID)

10706709
10978518
12477932
12826694
14702039
15489334
16344560
17207965
18392855

Gene Ontology  (GO ID)

Biological Process

GO:0070233  negative regulation of T cell apoptosis
GO:0045580  regulation of T cell differentiation
GO:0043029  T cell homeostasis
GO:0048538  thymus development
GO:0006810  transport

Cellular Component

GO:0009986  cell surface
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0015293  symporter activity