protein tyrosine phosphatase, receptor type, C

Synonym

CD45 antigen, L-CA, PTPRC, CD45, LY5, Leukocyte common antigen precursor, protein tyrosine phosphatase, receptor type, C, T200, B220, GP180

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:5.81

cerebellum:4.65

brain stem:6.26

corpus callosum/glia:7.75

pineal gland:-

peripheral nerve:7.16

spine:7.68

retina:-

eye:-

artery/aorta:6.55

vein:7.74

lymphnode:10.47

peripheral blood:-

spleen:11.32

thymus:11.59

bone marrow:10.45

adipose:7.66

bone:-

skin:6.79

CAGE

cerebrum:2.78

cerebellum:-

brain stem:3.61

corpus callosum/glia:3.10

pineal gland:2.70

peripheral nerve:-

spine:4.35

retina:-

eye:-

artery/aorta:3.47

vein:5.78

lymphnode:6.14

peripheral blood:-

spleen:6.37

thymus:6.87

bone marrow:-

adipose:4.22

bone:-

skin:-

RNA-seq

cerebrum:2.10

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.90

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.67

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:7.10

placenta:7.16

prostate:6.32

ovary:7.28

testis:4.70

heart:6.56

muscle:4.78

esophagus:6.87

stomach:8.61

intestine:7.45

colon:7.69

liver/hepato:8.17

lung:10.36

bladder:-

kidney:5.31

pituitary:4.61

thyroid/parathyroid:6.95

adrenal gland:6.14

pancreas:6.57

breast:7.55

salivary:5.96

CAGE

uterus:3.20

placenta:3.42

prostate:3.49

ovary:3.11

testis:2.72

heart:2.97

muscle:1.97

esophagus:3.56

stomach:-

intestine:4.16

colon:3.39

liver/hepato:3.46

lung:5.40

bladder:4.43

kidney:3.30

pituitary:2.45

thyroid/parathyroid:2.59

adrenal gland:-

pancreas:1.98

breast:2.53

salivary:3.56

RNA-seq

uterus:-

placenta:-

prostate:2.06

ovary:2.10

testis:1.81

heart:1.57

muscle:0.41

esophagus:-

stomach:-

intestine:-

colon:1.57

liver/hepato:1.76

lung:5.38

bladder:-

kidney:1.99

pituitary:-

thyroid/parathyroid:1.43

adrenal gland:5.32

pancreas:-

breast:2.31

salivary:-

IDs

Refseq ID	NM_080921
Gene ID	5788
Unigene ID	-
Probe set ID	212587_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000081237
GTEx ID	ENSG00000081237

Orthologous Gene

Mouse[2]	NM_001111316, NM_011210
Rat[16]	NM_001109887, NM_001109888, NM_001109889, NM_001109890, NM_138507

Chromosomal Region

1q31.3 [198,607,801 - 198,726,545]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR000242	Protein-tyrosine phosphatase, receptor/non-receptor type

Gene Ontology (GO ID)

Biological Process

GO:0007411	axon guidance
GO:0042100	B cell proliferation
GO:0050853	B cell receptor signaling pathway
GO:0048539	bone marrow development
GO:0007166	cell surface receptor linked signal transduction
GO:0051607	defense response to virus
GO:0016311	dephosphorylation
GO:0002244	hemopoietic progenitor cell differentiation
GO:0002378	immunoglobulin biosynthetic process
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0001960	negative regulation of cytokine-mediated signaling pathway
GO:0006469	negative regulation of protein kinase activity
GO:0001915	negative regulation of T cell mediated cytotoxicity
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway
GO:0030890	positive regulation of B cell proliferation
GO:0045860	positive regulation of protein kinase activity
GO:0042102	positive regulation of T cell proliferation
GO:0006470	protein amino acid dephosphorylation
GO:0051726	regulation of cell cycle
GO:0033261	regulation of S phase
GO:0051209	release of sequestered calcium ion into cytosol
GO:0048864	stem cell development
GO:0030217	T cell differentiation
GO:0050852	T cell receptor signaling pathway

Cellular Component

GO:0009897	external side of plasma membrane
GO:0005925	focal adhesion
GO:0005887	integral to plasma membrane
GO:0045121	membrane raft
GO:0005886	plasma membrane

Molecular Function

GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004725	protein tyrosine phosphatase activity
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity

protein tyrosine phosphatase, receptor type, C

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function